Cellosaurus NCI-H748 (CVCL_1588)

Cell line name NCI-H748
Synonyms H748; H-748
Accession CVCL_1588
Resource Identification Initiative To cite this cell line use: NCI-H748 (RRID:CVCL_1588)
Comments Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Disease Small cell lung carcinoma (NCIt: C4917)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A583 ! NCI-H792
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP

Markers:
AmelogeninX
CSF1PO11
D13S31711
D16S53912
D5S81810
D7S82010,11
TH017,9
TPOX10,12
vWA17,19
Publications

PubMed=8806092; DOI=10.1002/jcb.240630505
Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P., McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr., Carney D.N., Minna J.D., Mulshine J.L.
NCI-Navy Medical Oncology Branch cell line data base.
J. Cell. Biochem. 63 Suppl. 24:32-91(1996)

PubMed=8806103; DOI=10.1002/jcb.240630516
Johnson B.E., Russell E., Simmons A.M., Phelps R.M., Steinberg S.M., Ihde D.C., Gazdar A.F.
MYC family DNA amplification in 126 tumor cell lines from patients with small cell lung cancer.
J. Cell. Biochem. 63 Suppl. 24:210-217(1996)

PubMed=11030152; DOI=10.1038/sj.onc.1203815
Modi S., Kubo A., Oie H., Coxon A.B., Rehmatulla A., Kaye F.J.
Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer.
Oncogene 19:4632-4639(2000)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; CRL-5841
Cell line databases/resources Cosmic-CLP; 909194
GDSC; 909194
IGRhCellID; NCIH748
LINCS_LDP; LCL-1861
Ontologies CLO; CLO_0008115
EFO; EFO_0002304
Biological sample resources BioSample; SAMN03472833
Chemistry resources ChEMBL-Cells; CHEMBL3308298
ChEMBL-Targets; CHEMBL2366163
Gene expression databases GEO; GSM169444
GEO; GSM794300
GEO; GSM1670264
Polymorphism and mutation databases Cosmic; 688030
Cosmic; 844561
Cosmic; 877213
Cosmic; 877364
Cosmic; 909194
Cosmic; 980936
Cosmic; 1021870
Cosmic; 1032403
Cosmic; 1152477
Cosmic; 1759296
Cosmic; 1995591