Cellosaurus NEC8 (CVCL_1604)

Cell line name NEC8
Synonyms NEC-8
Accession CVCL_1604
Resource Identification Initiative To cite this cell line use: NEC8 (RRID:CVCL_1604)
Comments Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Testicular embryonal carcinoma (NCIt: C6341)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_IW43 (NEC8 cl-1)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB; RCB

Markers:
AmelogeninX
CSF1PO13,15
D13S31712
D16S5399,10
D5S81810,14
D7S8208
TH016,7
TPOX8,11
vWA14,15
Publications

PubMed=520758; DOI=10.20772/cancersci1959.70.5_677
Yamamoto T., Komatsubara S., Suzuki T., Oboshi S.
In vitro cultivation of human testicular embryonal carcinoma and establishment of a new cell line.
Gann 70:677-680(1979)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=2445169; DOI=10.1111/j.1440-1827.1987.tb00459.x
Motoyama T., Watanabe H., Yamamoto T., Sekiguchi M.
Production of alpha-fetoprotein by human germ cell tumors in vivo and in vitro.
Acta Pathol. Jpn. 37:1263-1277(1987)

PubMed=3618218; DOI=10.1111/j.1440-1827.1987.tb00377.x
Motoyama T., Watanabe H., Yamamoto T., Sekiguchi M.
Human testicular germ cell tumors in vitro and in athymic nude mice.
Acta Pathol. Jpn. 37:431-448(1987)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections JCRB; JCRB0250
RCB; RCB0489
Cell line databases/resources Cosmic-CLP; 910942
GDSC; 910942
LINCS_LDP; LCL-1900
Ontologies CLO; CLO_0051391
Biological sample resources BioSample; SAMN03471665
Chemistry resources ChEMBL-Cells; CHEMBL3308176
ChEMBL-Targets; CHEMBL2366340
Gene expression databases GEO; GSM827251
GEO; GSM1670276
Polymorphism and mutation databases Cosmic; 910942