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Cellosaurus NH-12 (CVCL_1605)

[Text version]

Cell line name NH-12
Synonyms NH12
Accession CVCL_1605
Resource Identification Initiative To cite this cell line use: NH-12 (RRID:CVCL_1605)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North74.87
East Asian, South25.12
South Asian0
European, North0
European, South0
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 1Y3M
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB; RCB; TKG

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81810,11
D7S82011,13
D13S3178,9
D16S53911
TH019,10
TPOX8
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=12210830; DOI=10.1002/jnr.10330
Yoshida S., Narita T., Taga T., Ohta S., Takeuchi Y.
Malignant rhabdoid tumor shows incomplete neural characteristics as revealed by expression of SNARE complex.
J. Neurosci. Res. 69:642-652(2002)

PubMed=18923524; DOI=10.1038/nature07399
Chen Y., Takita J., Choi Y.L., Kato M., Ohira M., Sanada M., Wang L., Soda M., Kikuchi A., Igarashi T., Nakagawara A., Hayashi Y., Mano H., Ogawa S.
Oncogenic mutations of ALK kinase in neuroblastoma.
Nature 455:971-974(2008)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections JCRB; JCRB0833
RCB; RCB2108
TKG; TKG 0448
Cell line databases/resources CCLE; NH12_AUTONOMIC_GANGLIA
Cell_Model_Passport; SIDM00577
Cosmic-CLP; 908447
DepMap; ACH-001603
LINCS_LDP; LCL-1978
Ontologies CLO; CLO_0050267
Biological sample resources BioSample; SAMN01821709
BioSample; SAMN03472526
Chemistry resources ChEMBL-Cells; CHEMBL3308211
ChEMBL-Targets; CHEMBL2366263
GDSC; 908447
PharmacoDB; NH12_1157_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM313808
GEO; GSM333802
GEO; GSM1670277
Other Wikidata; Q54930502
Polymorphism and mutation databases Cosmic; 801745
Cosmic; 908447
Cosmic; 947719
Cosmic; 1037350
Cosmic; 1099147
Cosmic; 1153788
Cosmic; 2131593
Entry history
Entry creation04-Apr-2012
Last entry updated12-Mar-2020
Version number28