Cellosaurus NKM-1 (CVCL_1607)

Cell line name NKM-1
Synonyms NKM1
Accession CVCL_1607
Resource Identification Initiative To cite this cell line use: NKM-1 (RRID:CVCL_1607)
Comments Doubling time: 36-48 hours (PubMed=1701353).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Derived from sampling site: Peripheral blood.
Disease Adult acute myeloid leukemia (NCIt: C9154)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB

Markers:
AmelogeninX
CSF1PO10
D13S31711,13
D16S5399,12
D5S81810,12
D7S82010,11
TH016,9
TPOX9,11
vWA17
Publications

PubMed=1699657
Towatari M., Ito Y., Morishita Y., Tanimoto M., Kawashima K., Morishima Y., Andoh T., Saito H.
Enhanced expression of DNA topoisomerase II by recombinant human granulocyte colony-stimulating factor in human leukemia cells.
Cancer Res. 50:7198-7202(1990)

PubMed=1701353
Kataoka T., Morishita Y., Ogura M., Morishima Y., Towatari M., Kato Y., Inoue H., Saito H.
A novel human myeloid leukemia cell line, NKM-1, coexpressing granulocyte colony-stimulating factor receptors and macrophage colony-stimulating factor receptors.
Cancer Res. 50:7703-7709(1990)

PubMed=1701357
Morishita Y., Kataoka T., Towatari M., Ito T., Inoue H., Ogura M., Morishima Y., Saito H.
Up-regulation of transferrin receptor gene expression by granulocyte colony-stimulating factor in human myeloid leukemia cells.
Cancer Res. 50:7955-7961(1990)

PubMed=9737686; DOI=10.1038/sj.leu.2401112
Zhang W., Ohnishi K., Shigeno K., Fujisawa S., Naito K., Nakamura S., Takeshita K., Takeshita A., Ohno R.
The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms.
Leukemia 12:1383-1391(1998)

PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x
Takizawa J., Suzuki R., Kuroda H., Utsunomiya A., Kagami Y., Joh T., Aizawa Y., Ueda R., Seto M.
Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia.
Jpn. J. Cancer Res. 89:712-718(1998)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections IFO; IFO50476
Cell line databases/resources Cosmic-CLP; 908448
GDSC; 908448
LINCS_LDP; LCL-1073
Biological sample resources BioSample; SAMN03472796
Chemistry resources ChEMBL-Cells; CHEMBL3308212
ChEMBL-Targets; CHEMBL2366133
Gene expression databases GEO; GSM1670279
Polymorphism and mutation databases Cosmic; 908448
Cosmic; 1523824
Cosmic; 2131549
Cosmic; 2306228