Cellosaurus NMC-G1 (CVCL_1608)

Cell line name NMC-G1
Synonyms NMCG-1; NMCG1; National Medical Center-Glioma 1
Accession CVCL_1608
Resource Identification Initiative To cite this cell line use: NMC-G1 (RRID:CVCL_1608)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Astrocytoma (NCIt: C60781)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB

Markers:
AmelogeninX
CSF1PO12
D13S31711,13
D16S53910,13
D5S81812
D7S8208,12
TH019,9.3
TPOX8,9
vWA17,18
Publications

DOI=10.1007/978-4-431-68150-2_30
Shinoura N., Kondo T., Yoshioka M.
Measuring the effect of PDGF on fibroblasts using glioma cell lines.
(In) Biological aspects of brain tumors. Proceedings of the 8th Nikko brain tumor conference, Karatsu (Saga) 1990; Tabuchi K. (eds.); pp.235-243; Springer; Tokyo (1991)

PubMed=8428960
Naruo K.-I., Seko C., Kuroshima K.-I., Matsutani E., Sasada R., Kondo T., Kurokawa T.
Novel secretory heparin-binding factors from human glioma cells (glia-activating factors) involved in glial cell growth. Purification and biological properties.
J. Biol. Chem. 268:2857-2864(1993)

PubMed=16232199; DOI=10.1111/j.1349-7006.2005.00099.x
Saigusa K., Hashimoto N., Tsuda H., Yokoi S., Maruno M., Yoshimine T., Aoyagi M., Ohno K., Imoto I., Inazawa J.
Overexpressed Skp2 within 5p amplification detected by array-based comparative genomic hybridization is associated with poor prognosis of glioblastomas.
Cancer Sci. 96:676-683(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections IFO; IFO50467
Cell line databases/resources CCLE; NMCG1_CENTRAL_NERVOUS_SYSTEM
CGH-DB; 150-1
Cosmic-CLP; 908449
GDSC; 908449
LINCS_LDP; LCL-1385
Biological sample resources BioSample; SAMN03472793
Chemistry resources ChEMBL-Cells; CHEMBL3308842
ChEMBL-Targets; CHEMBL2366349
Gene expression databases GEO; GSM326197
GEO; GSM887457
GEO; GSM888537
GEO; GSM1670280
Polymorphism and mutation databases Cosmic; 685874
Cosmic; 908449
Cosmic; 1746963
Cosmic; 2302335
Cosmic; 2367540