Cellosaurus NOMO-1 (CVCL_1609)

Cell line name NOMO-1
Synonyms Nomo-1; NOMO1
Accession CVCL_1609
Resource Identification Initiative To cite this cell line use: NOMO-1 (RRID:CVCL_1609)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 55 hours (PubMed=25984343); ~35 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: shRNA library screening.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Bone marrow.
Disease Adult acute monocytic leukemia (NCIt: C8263)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_3077 (NOMO-1/ADM); CVCL_3078 (NOMO-1s)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; JCRB; PubMed=25877200

Markers:
AmelogeninX
CSF1PO11,12
D13S3178,10
D16S5399,11
D18S5117,22
D21S1129,32.2
D3S135815,17
D5S81811,13
D7S8208,10
D8S117913,14
FGA21,22
Penta D9,12
Penta E15,17
TH016,9
TPOX8,12
vWA17,18
Publications

DOI=10.3960/jslrt1961.28.19
Ogura M., Hamaguchi M.
Coagulation and fibrinolysis system of a human monocytic leukemia cell line, NOMO-1.
Nihon Monaikei Gakkai Kaishi 28:19-26(1988)

PubMed=1699657
Towatari M., Ito Y., Morishita Y., Tanimoto M., Kawashima K., Morishima Y., Andoh T., Saito H.
Enhanced expression of DNA topoisomerase II by recombinant human granulocyte colony-stimulating factor in human leukemia cells.
Cancer Res. 50:7198-7202(1990)

PubMed=1701357
Morishita Y., Kataoka T., Towatari M., Ito T., Inoue H., Ogura M., Morishima Y., Saito H.
Up-regulation of transferrin receptor gene expression by granulocyte colony-stimulating factor in human myeloid leukemia cells.
Cancer Res. 50:7955-7961(1990)

PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x
Takizawa J., Suzuki R., Kuroda H., Utsunomiya A., Kagami Y., Joh T., Aizawa Y., Ueda R., Seto M.
Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia.
Jpn. J. Cancer Res. 89:712-718(1998)

PubMed=14671638; DOI=10.1038/sj.leu.2403236
Drexler H.G., Quentmeier H., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations.
Leukemia 18:227-232(2004)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-542
IFO; IFO50474
Cell line databases/resources CCLE; NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cosmic-CLP; 908451
GDSC; 908451
LINCS_LDP; LCL-1074
Ontologies BTO; BTO:0005916
Biological sample resources BioSample; SAMN01821652
BioSample; SAMN01821737
BioSample; SAMN03473105
Chemistry resources ChEMBL-Cells; CHEMBL3308243
ChEMBL-Targets; CHEMBL2366198
Gene expression databases GEO; GSM236799
GEO; GSM236835
GEO; GSM482496
GEO; GSM887458
GEO; GSM888538
GEO; GSM1374774
GEO; GSM1446755
GEO; GSM1670283
Polymorphism and mutation databases Cosmic; 787464
Cosmic; 908451
Cosmic; 975286
Cosmic; 1281342
Cosmic; 1523827
Cosmic; 1524839
Cosmic; 2131550
Cosmic; 2297030
Cosmic; 2306229