ID   OC 315
AC   CVCL_1617
SY   OC-315; OC315
DR   BTO; BTO:0006436
DR   CLO; CLO_0008232
DR   cancercelllines; CVCL_1617
DR   Cell_Model_Passport; SIDM01823
DR   DepMap; ACH-001144
DR   GEO; GSM459737
DR   ICLC; HTL98013
DR   PharmacoDB; OC315_1180_2019
DR   Progenetix; CVCL_1617
DR   Wikidata; Q54931702
RX   PubMed=8690298;
RX   PubMed=15677628;
RX   PubMed=31068700;
CC   Problematic cell line: Possibly contaminated. May be identical to OC 314 (Cellosaurus=CVCL_1616) according to STR profiling done at ICLC and to MSI data (PubMed=15677628).
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Microsatellite instability: Instable (MSI-high) (PubMed=15677628).
CC   Discontinued: ICLC; HTL98013; true.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C7550; Ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   49Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 20
//
RX   PubMed=8690298; DOI=10.1006/gyno.1996.0194;
RA   Alama A., Barbieri F., Favre A., Cagnoli M., Noviello E., Pedulla F.,
RA   Viale M., Foglia G., Ragni N.;
RT   "Establishment and characterization of three new cell lines derived
RT   from the ascites of human ovarian carcinomas.";
RL   Gynecol. Oncol. 62:82-88(1996).
//
RX   PubMed=15677628; DOI=10.1093/carcin/bgi032;
RA   Gorringe K.L., Chin S.-F., Pharoah P.D.P., Staines J.M., Oliveira C.,
RA   Edwards P.A.W., Caldas C.;
RT   "Evidence that both genetic instability and selection contribute to
RT   the accumulation of chromosome alterations in cancer.";
RL   Carcinogenesis 26:923-930(2005).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//