Cellosaurus OCUB-M (CVCL_1621)

Cell line name OCUB-M
Synonyms OCUB-1M
Accession CVCL_1621
Resource Identification Initiative To cite this cell line use: OCUB-M (RRID:CVCL_1621)
Comments Part of: COSMIC cell lines project.
Microsatellite instability: Instable (MSI-low) (PubMed=15677628; Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Disease Breast carcinoma (NCIt: C4872)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_L114 (OCUB-1)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB

Markers:
AmelogeninX
CSF1PO10,11
D13S3178
D16S53911
D5S81810
D7S8209,13
TH019
TPOX7,8
vWA18
Publications

PubMed=7873497
Sawada T., Chung Y.-S., Nakata B., Kubo T., Kondo Y., Sogabe T., Onoda N., Ogawa Y., Yamada N., Sowa M.
Establishment and characterization of a human breast cancer cell line, OCUB-1.
Hum. Cell 7:138-144(1994)

PubMed=15677628; DOI=10.1093/carcin/bgi032
Gorringe K.L., Chin S.-F., Pharoah P., Staines J.M., Oliveira C., Edwards P.A.W., Caldas C.
Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer.
Carcinogenesis 26:923-930(2005)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections RCB; RCB0881
Cell line databases/resources Cosmic-CLP; 909256
GDSC; 909256
LINCS_LDP; LCL-1489
Ontologies CLO; CLO_0051609
Biological sample resources BioSample; SAMN03472188
Chemistry resources ChEMBL-Cells; CHEMBL3308245
ChEMBL-Targets; CHEMBL2366121
Gene expression databases GEO; GSM217594
GEO; GSM1661987
GEO; GSM1670300
Polymorphism and mutation databases Cosmic; 909256