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Cellosaurus P30/OHK (CVCL_1631)

[Text version]

Cell line name P30/OHK
Synonyms P30-OHK; P30 OHK; P30OHK; P30/Ohkubo; P30/OHKUBO; P30-OHKUBO; P30/0HK
Accession CVCL_1631
Resource Identification Initiative To cite this cell line use: P30/OHK (RRID:CVCL_1631)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: ~30 hours (PubMed=6983990); ~30 hours (DSMZ).
Microsatellite instability: Instable (MSI-high) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Bone marrow.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 11Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; JCRB; RCB; TKG

Markers:
AmelogeninX
CSF1PO9,11
D5S81811,12
D7S82010,11
D13S31710
D16S5399
TH019
TPOX10,11
vWA14,21

Run an STR similarity search on this cell line
Publications

PubMed=6983990
Hirose M., Minato K., Tobinai K., Ohira M., Ise T., Watanabe S., Shimoyama M., Taniwaki M., Abe T.
A novel pre-T cell line derived from acute lymphoblastic leukemia.
Gann 73:600-605(1982)

PubMed=9680106; DOI=10.1016/S0145-2126(98)00050-2
Matsuo Y., Drexler H.G.
Establishment and characterization of human B cell precursor-leukemia cell lines.
Leuk. Res. 22:567-579(1998)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-727
JCRB; JCRB0094
RCB; RCB1938
TKG; TKG 0463
Cell line databases/resources CCLE; P30OHK_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cell_Model_Passport; SIDM00364
Cosmic-CLP; 909252
GDSC; 909252
LINCS_LDP; LCL-1038
Ontologies CLO; CLO_0051011
Biological sample resources BioSample; SAMN01821712
BioSample; SAMN03471069
Chemistry resources ChEMBL-Cells; CHEMBL3308275
ChEMBL-Targets; CHEMBL2366165
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM827254
GEO; GSM1670327
Other Wikidata; Q54937245
Polymorphism and mutation databases Cosmic; 909252
Cosmic; 919141
Cosmic; 998703
Cosmic; 1037718