Cell line name | PF-382 | ||||||||||||||||||
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Synonyms | PF382 | ||||||||||||||||||
Accession | CVCL_1641 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: PF-382 (RRID:CVCL_1641) | ||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Doubling time: 40 hours (PubMed=2410652); ~70 hours (DSMZ). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. Derived from sampling site: Pleural effusion. | ||||||||||||||||||
Sequence variations | Heterozygous for NOTCH1 p.Leu1574Pro (c.4721T>C) and p.Pro2493fs*67 (c.7476_7477ins11) (PubMed=15472075).Heterozygous for TP53 p.Arg273Cys (c.817C>T) (ClinVar=VCV000043594) (Cosmic-CLP). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Hierarchy | Children:
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Sex of cell | Female | ||||||||||||||||||
Age at sampling | 6Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP; DSMZ Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=2410652; DOI=10.1093/jnci/75.2.285 PubMed=3499548 DOI=10.1016/B978-0-12-221970-2.50457-5 PubMed=15472075; DOI=10.1126/science.1102160 PubMed=15843827; DOI=10.1038/sj.leu.2403749 PubMed=16408098; DOI=10.1038/sj.leu.2404081 PubMed=17170727; DOI=10.1038/sj.leu.2404486 PubMed=20164919; DOI=10.1038/nature08768 PubMed=22460905; DOI=10.1038/nature11003 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30285677; DOI=10.1186/s12885-018-4840-5 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | DSMZ; ACC-38
ICLC; HTL00006 | ||||||||||||||||||
Cell line databases/resources | CLDB; cl3895
CLDB; cl4993 CCLE; PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE Cell_Model_Passport; SIDM00451 Cosmic-CLP; 909260 DepMap; ACH-000937 LINCS_LDP; LCL-1021 | ||||||||||||||||||
Ontologies | CLO; CLO_0008421 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03473327
BioSample; SAMN10988497 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308246
ChEMBL-Targets; CHEMBL2366235 GDSC; 909260 PharmacoDB; PF382_1262_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-2770 ArrayExpress; E-MTAB-3610 GEO; GSM887513 GEO; GSM888595 GEO; GSM1670348 | ||||||||||||||||||
Other | Wikidata; Q54947238 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 909260
Cosmic; 913414 Cosmic; 1012113 Cosmic; 1115593 Cosmic; 1151790 Cosmic; 1224370 Cosmic; 1524814 Cosmic; 1641384 Cosmic; 2165708 IARC_TP53; 21278 LiGeA; CCLE_260 Progenetix; CVCL_1641 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 29-Oct-2020 | ||||||||||||||||||
Version number | 29 |