Cellosaurus PF-382 (CVCL_1641)

Cell line name PF-382
Synonyms PF382
Accession CVCL_1641
Resource Identification Initiative To cite this cell line use: PF-382 (RRID:CVCL_1641)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~70 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Pleural fluid.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_H267 (ST-4)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ

Markers:
AmelogeninX
CSF1PO10,13
D13S31711,12
D16S5399,12
D5S81811,12
D7S8209,10
TH016,9.3
TPOX11
vWA16,17
Publications

PubMed=2410652; DOI=10.1093/jnci/75.2.285
Pegoraro L., Fierro M.T., Lusso P., Giovinazzo B., Lanino E., Giovarelli M., Matera L., Foa R.
A novel leukemia T-cell line (PF-382) with phenotypic and functional features of suppressor lymphocytes.
J. Natl. Cancer Inst. 75:285-290(1985)

PubMed=3499548
Bellone G., Foa R., Fierro M.T., Avanzi G.C., Lusso P., Ramello A., Lista P., Ghio R., Pegoraro L.
A human leukemic T cell line (PF-382) inhibits the growth of myeloid and erythroid progenitor cells.
Leukemia 1:603-608(1987)

PubMed=15843827; DOI=10.1038/sj.leu.2403749
Andersson A., Eden P., Lindgren D., Nilsson J., Lassen C., Heldrup J., Fontes M., Borg A., Mitelman F., Johansson B., Hoglund M., Fioretos T.
Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations.
Leukemia 19:1042-1050(2005)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-38
ICLC; HTL00006
Cell line databases/resources CLDB; cl3895
CLDB; cl4993
CCLE; PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cosmic-CLP; 909260
GDSC; 909260
LINCS_LDP; LCL-1021
Ontologies CLO; CLO_0008421
Biological sample resources BioSample; SAMN03473327
Chemistry resources ChEMBL-Cells; CHEMBL3308246
ChEMBL-Targets; CHEMBL2366235
Gene expression databases GEO; GSM887513
GEO; GSM888595
GEO; GSM1670348
Polymorphism and mutation databases Cosmic; 909260
Cosmic; 913414
Cosmic; 1012113
Cosmic; 1115593
Cosmic; 1151790
Cosmic; 1224370
Cosmic; 1524814
Cosmic; 1641384
Cosmic; 2165708