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Cellosaurus Ramos.2G6.4C10 (CVCL_1646)

[Text version]

Cell line name Ramos.2G6.4C10
Synonyms RAMOS.2G6.4C10; Ramos-2G6-4C10; RAMOS-2G6-4C10; Ramos 2G6.4C10; Ramos 2G6 4C10; RAMOS2G64C10; Ramos.G6.C10; Ramos G6.C10
Accession CVCL_1646
Resource Identification Initiative To cite this cell line use: Ramos.2G6.4C10 (RRID:CVCL_1646)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Population: Caucasian.
Characteristics: EBV-negative.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Ascites.
Sequence variations MYC-IGH gene fusion (from parent cell line).
Homozygous for TP53 p.Ile254Asp (c.760_761AT>GA) (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African4.71
Native American43.61
East Asian, North3.64
East Asian, South0
South Asian0
European, North22.74
European, South25.29
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0597 (Ramos)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP

Markers:
AmelogeninX
CSF1PO10,11
D5S8187,12
D7S82011
D13S31713
D16S53910,13
TH017,9.3
TPOX8,9
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=1698879; DOI=10.1016/0022-1759(90)90040-3
Siegel J.P., Mostowski H.S.
A bioassay for the measurement of human interleukin-4.
J. Immunol. Methods 132:287-295(1990)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections ATCC; CRL-1923
Cell line databases/resources CCLE; RAMOS2G64C10_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cell_Model_Passport; SIDM01247
Cosmic-CLP; 910401
DepMap; ACH-002300
LINCS_LDP; LCL-2027
Ontologies CLO; CLO_0008740
Biological sample resources BioSample; SAMN03471265
Chemistry resources ChEMBL-Cells; CHEMBL3308341
ChEMBL-Targets; CHEMBL2366170
GDSC; 910401
PharmacoDB; Ramos2G64C10_1284_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1670358
Other Wikidata; Q54949208
Polymorphism and mutation databases Cosmic; 687851
Cosmic; 910401
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number25