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Cellosaurus Ramos.2G6.4C10 (CVCL_1646)

[Text version]

Cell line name Ramos.2G6.4C10
Synonyms RAMOS.2G6.4C10; Ramos-2G6-4C10; RAMOS-2G6-4C10; Ramos 2G6.4C10; Ramos 2G6 4C10; RAMOS2G64C10; Ramos.G6.C10; Ramos G6.C10
Accession CVCL_1646
Resource Identification Initiative To cite this cell line use: Ramos.2G6.4C10 (RRID:CVCL_1646)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Population: Caucasian.
Characteristics: EBV-negative.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Ascites.
Sequence variations Gene fusion; HGNC; 5477; IGH + HGNC; 7553; MYC; Name(s)=MYC-IGH (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Ile254Asp (c.760_761AT>GA); Zygosity=Homozygous (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American43.61
East Asian, North3.64
East Asian, South0
South Asian0
European, North22.74
European, South25.29
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0597 (Ramos)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP


Run an STR similarity search on this cell line

PubMed=1698879; DOI=10.1016/0022-1759(90)90040-3
Siegel J.P., Mostowski H.S.
A bioassay for the measurement of human interleukin-4.
J. Immunol. Methods 132:287-295(1990)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cell line collections ATCC; CRL-1923
Cell_Model_Passport; SIDM01247
Cosmic-CLP; 910401
DepMap; ACH-002300
Ontologies CLO; CLO_0008740
Biological sample resources BioSample; SAMN03471265
Chemistry resources ChEMBL-Cells; CHEMBL3308341
ChEMBL-Targets; CHEMBL2366170
GDSC; 910401
PharmacoDB; Ramos2G64C10_1284_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1670358
Other Wikidata; Q54949208
Polymorphism and mutation databases Cosmic; 687851
Cosmic; 910401
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number28