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Cellosaurus RF-48 (CVCL_1657)

[Text version]

Cell line name RF-48
Synonyms RF48
Accession CVCL_1657
Resource Identification Initiative To cite this cell line use: RF-48 (RRID:CVCL_1657)
Comments Problematic cell line: Misidentified. From a B-cell lymphoma and not from a gastric cancer (PubMed=12226758).
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African5.29
Native American31.68
East Asian, North3.25
East Asian, South0
South Asian2.87
European, North27.68
European, South29.24
Disease Lymphoma (NCIt: C3208)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_3580 ! RF-1
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO11
D5S81811,12
D7S82010,12
D13S31712
D16S53911,13
TH017,8
TPOX8,12
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=12226758; DOI=10.1038/sj.onc.1205829
Ji J., Chen X., Leung S.Y., Chi J.-T.A., Chu K.M., Yuen S.T., Li R., Chan A.S.Y., Li J., Dunphy N., So S.
Comprehensive analysis of the gene expression profiles in human gastric cancer cell lines.
Oncogene 21:6549-6556(2002)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections ATCC; CRL-1863 - Discontinued
IZSLER; BS TCL 208
Cell line databases/resources CCLE; RF48_STOMACH
Cell_Model_Passport; SIDM01092
Cosmic-CLP; 909697
DepMap; ACH-002301
GDSC; 909697
LINCS_LDP; LCL-1896
Biological sample resources BioSample; SAMN03471256
Chemistry resources PharmacoDB; RF48_1309_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670375
Other Wikidata; Q54949801
Polymorphism and mutation databases Cosmic; 909697
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number22