Cellosaurus RPMI-8402 (CVCL_1667)

Cell line name RPMI-8402
Synonyms RPMI 8402; RPMI8402; Roswell Park Memorial Institute 8402
Accession CVCL_1667
Resource Identification Initiative To cite this cell line use: RPMI-8402 (RRID:CVCL_1667)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~48 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children: CVCL_2878 (CPT-K5)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP; DSMZ

Markers:
AmelogeninX
CSF1PO11,12
D13S31711,12 (ATCC; DSMZ)
12 (Cosmic-CLP)
D16S53910,11
D5S81812,13
D7S8208,13
TH019,9.3
TPOX8
vWA14,20
Publications

CLPUB00338
Moore G.E., Woods L.K., Minowada J., Mitchen J.R.
Establishment of leukemia cell line with T cell characteristics.
In Vitro 8:434-434(1973)

DOI=10.1007/978-1-4757-1647-4_11
Moore G.E.
Cell lines from humans with hematopoietic malignancies.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.299-331; Springer; New York (1975)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=9933131; DOI=10.1016/S0145-2126(98)00133-7
Burger R., Hansen-Hagge T.E., Drexler H.G., Gramatzki M.
Heterogeneity of T-acute lymphoblastic leukemia (T-ALL) cell lines: suggestion for classification by immunophenotype and T-cell receptor studies.
Leuk. Res. 23:19-27(1999)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; CRL-1994 - Discontinued
DSMZ; ACC-290
NCBI_Iran; C184
Cell line databases/resources CCLE; RPMI8402_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cosmic-CLP; 909702
GDSC; 909702
LINCS_LDP; LCL-1022
Ontologies BTO; BTO:0001880
CLO; CLO_0008874
Biological sample resources BioSample; SAMN03471272
Chemistry resources ChEMBL-Cells; CHEMBL3307964
ChEMBL-Targets; CHEMBL612517
Gene expression databases GEO; GSM887549
GEO; GSM888632
GEO; GSM1670390
Polymorphism and mutation databases Cosmic; 801732
Cosmic; 909702
Cosmic; 913427
Cosmic; 932767
Cosmic; 998726
Cosmic; 999753
Cosmic; 1012115
Cosmic; 1037681
Cosmic; 1115587
Cosmic; 1151791
Cosmic; 1175132
Cosmic; 1191706
Cosmic; 1224369
Cosmic; 1281383
Cosmic; 1330501
Cosmic; 1524817
Cosmic; 1641386
Cosmic; 1664527
Cosmic; 2458761
Cosmic; 2462860
Cosmic; 2602930