Cellosaurus RPMI-8866 (CVCL_1668)

Cell line name RPMI-8866
Synonyms RPMI 8866; RPMI8866; Roswell Park Memorial Institute 8866; R8866
Accession CVCL_1668
Resource Identification Initiative To cite this cell line use: RPMI-8866 (RRID:CVCL_1668)
Comments Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Derived from sampling site: Peripheral blood.
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Transformed cell line
STR profile Source(s): Cosmic-CLP; ECACC; PubMed=17254797

Markers:
AmelogeninX
CSF1PO11
D13S31710,14
D16S53911
D18S5112,15
D21S1127,29
D3S135815,16
D5S81812
D7S82011,12
D8S117912,14
FGA22,23
TH019.3 (Cosmic-CLP; ECACC)
10 (PubMed=17254797)
TPOX8,11
vWA14,16
Publications

PubMed=4169031
Finegold I., Fahey J.L., Granger H.
Synthesis of immunoglobulins by human cell lines in tissue culture.
J. Immunol. 99:839-848(1967)

DOI=10.1007/978-1-4757-1647-4_11
Moore G.E.
Cell lines from humans with hematopoietic malignancies.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.299-331; Springer; New York (1975)

PubMed=17254797; DOI=10.1016/j.biologicals.2006.10.001
Azari S., Ahmadi N., Tehrani M.J., Shokri F.
Profiling and authentication of human cell lines using short tandem repeat (STR) loci: report from the National Cell Bank of Iran.
Biologicals 35:195-202(2007)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ECACC; 95041316
Cell line databases/resources CLDB; cl4186
Cosmic-CLP; 910544
GDSC; 910544
LINCS_LDP; LCL-1113
Ontologies BTO; BTO:0004206
CLO; CLO_0008875
Chemistry resources ChEMBL-Cells; CHEMBL3308323
ChEMBL-Targets; CHEMBL2366341
Gene expression databases GEO; GSM1670391
Polymorphism and mutation databases Cosmic; 910544