ID   RT-112
AC   CVCL_1670
SY   RT 112; RT112
DR   BTO; BTO:0003724
DR   CLO; CLO_0008890
DR   EFO; EFO_0006479
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2706
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   BioGRID_ORCS_Cell_line; 383
DR   BioSample; SAMN03473091
DR   BioSample; SAMN03473589
DR   BioSample; SAMN10988358
DR   cancercelllines; CVCL_1670
DR   Cell_Model_Passport; SIDM00402
DR   ChEMBL-Cells; CHEMBL3307307
DR   ChEMBL-Targets; CHEMBL614145
DR   CLS; 300324
DR   Cosmic; 715739
DR   Cosmic; 760482
DR   Cosmic; 845559
DR   Cosmic; 867837
DR   Cosmic; 909704
DR   Cosmic; 925820
DR   Cosmic; 928823
DR   Cosmic; 1046682
DR   Cosmic; 1068092
DR   Cosmic; 1285124
DR   Cosmic; 1285984
DR   Cosmic; 1819324
DR   Cosmic; 1938478
DR   Cosmic; 1938697
DR   Cosmic; 2037954
DR   Cosmic; 2050459
DR   Cosmic; 2057454
DR   Cosmic; 2444244
DR   Cosmic; 2686111
DR   Cosmic-CLP; 909704
DR   DepMap; ACH-000473
DR   DSMZ; ACC-418
DR   DSMZCellDive; ACC-418
DR   EGA; EGAS00001000610
DR   EGA; EGAS00001000978
DR   GDSC; 909704
DR   GEO; GSM887552
DR   GEO; GSM888635
DR   GEO; GSM1374857
DR   GEO; GSM1374858
DR   GEO; GSM1574545
DR   GEO; GSM1574581
DR   GEO; GSM1670393
DR   IARC_TP53; 13322
DR   LiGeA; CCLE_846
DR   LINCS_LDP; LCL-1716
DR   PharmacoDB; RT112_1332_2019
DR   PRIDE; PXD030304
DR   Progenetix; CVCL_1670
DR   PubChem_Cell_line; CVCL_1670
DR   Wikidata; Q54951347
RX   PubMed=571047;
RX   PubMed=864752;
RX   PubMed=870558;
RX   PubMed=2144165;
RX   PubMed=2903891;
RX   PubMed=3708594;
RX   PubMed=6823318;
RX   PubMed=7490993;
RX   PubMed=8873383;
RX   PubMed=11207054;
RX   PubMed=11416159;
RX   PubMed=11921286;
RX   PubMed=12127398;
RX   PubMed=15846775;
RX   PubMed=20164919;
RX   PubMed=22460905;
RX   PubMed=24018021;
RX   PubMed=24035680;
RX   PubMed=24367658;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=25984343;
RX   PubMed=25997541;
RX   PubMed=26055179;
RX   PubMed=26589293;
RX   PubMed=27270441;
RX   PubMed=27397505;
RX   PubMed=28855393;
RX   PubMed=29732388;
RX   PubMed=30894373;
RX   PubMed=31068700;
RX   PubMed=31395879;
RX   PubMed=31978347;
RX   PubMed=35839778;
WW   http://faculty.washington.edu/trawets/archive/Human/bladder/rt112/index.html
WW   https://www.synapse.org/UC25
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Part of: TCGA-110-CL cell line panel.
CC   Part of: UBC-40 urothelial bladder cancer cell line index.
CC   Population: Caucasian.
CC   Doubling time: 24 hours (PubMed=3708594); 25 hours (PubMed=25984343); 25.7 hours (PubMed=26055179); 21.6 +- 0.1 hours (PubMed=2144165); ~35 hours (DSMZ=ACC-418).
CC   HLA typing: A*26:01,26:01; B*08:01,27:05; C*01:02,01:02; DRB1*03:17,15:01 (PubMed=26589293).
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Gene fusion; HGNC; 3690; FGFR3 + HGNC; 11524; TACC3; Name(s)=FGFR3-TACC3 (PubMed=25485619; PubMed=28855393).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=24035680; PubMed=31068700).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser183Ter (c.548C>G); ClinVar=VCV000634701; Zygosity=Heterozygous (Cosmic-CLP; DepMap).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (Cosmic-CLP; DepMap).
CC   Omics: CNV analysis.
CC   Omics: Deep exome analysis.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: shRNA library screening.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Genome ancestry: African=0%; Native American=0%; East Asian, North=1.6%; East Asian, South=0%; South Asian=0%; European, North=65.6%; European, South=32.8% (PubMed=30894373).
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
ST   Source(s): CLS; Cosmic-CLP; DSMZ; PubMed=11416159; PubMed=25877200; PubMed=27270441
ST   Amelogenin: X
ST   CSF1PO: 10 (PubMed=25877200)
ST   CSF1PO: 10,11 (CLS; Cosmic-CLP; DSMZ; PubMed=27270441)
ST   D13S317: 13,14
ST   D16S539: 11,13
ST   D18S51: 15 (CLS)
ST   D18S51: 15,17 (DSMZ; PubMed=25877200)
ST   D19S433: 13,15
ST   D21S11: 27,30
ST   D2S1338: 17,24
ST   D3S1358: 15
ST   D5S818: 10,13
ST   D7S820: 11,12
ST   D8S1179: 13,15
ST   FGA: 23 (CLS)
ST   FGA: 23,25 (DSMZ; PubMed=25877200)
ST   Penta D: 10 (DSMZ; PubMed=25877200)
ST   Penta D: 10,11 (CLS)
ST   Penta E: 12,16
ST   TH01: 7
ST   TPOX: 8,11
ST   vWA: 14,17
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 42
//
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RT   cancer and detection of mutations in voided urine.";
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RT   urothelial cancer.";
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//