Cellosaurus SAS (CVCL_1675)

Cell line name SAS
Accession CVCL_1675
Resource Identification Initiative To cite this cell line use: SAS (RRID:CVCL_1675)
Comments Doubling time: 33 hours (PubMed=24627082).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_R859 (SAS-H1)CVCL_R860 (SAS-L1)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB; RCB; TKG

Markers:
AmelogeninX
CSF1PO11
D13S31710,12
D16S53912,13
D5S8189
D7S82011,12
TH016,7
TPOX11,12
vWA10,14 (Cosmic-CLP)
10,14,17 (JCRB)
14,17 (RCB; TKG)
Publications

DOI=10.11277/stomatology1952.38.20
Takahashi K., Kanazawa H., Akiyama Y., Tazaki S., Takahara M., Muto T., Tanzawa H., Sato K.-I.
Establishment and characterization of a cell line (SAS) from poorly differentiated human squamous cell carcinoma of the tongue.
J. Jpn. Stomatol. Soc. 38:20-28(1989)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

DOI=10.5843/jsot.13.Suppliment_301
Tadateru A., Tarou I., Tachikawa T.
Establishment and charactalization of human oral squamous cell carcinoma cell line with highly lymph node metastatic potential.
J. Jpn. Soc. Oral Oncol. 13 Suppl. 1:301-306(2001)

PubMed=17325662; DOI=10.1038/sj.onc.1210330
Nakaya K., Yamagata H.D., Arita N., Nakashiro K.-I., Nose M., Miki T., Hamakawa H.
Identification of homozygous deletions of tumor suppressor gene FAT in oral cancer using CGH-array.
Oncogene 26:5300-5308(2007)

PubMed=24627082; DOI=10.3892/ijo.2014.2332
Fujinaga T., Kumamaru W., Sugiura T., Kobayashi Y., Ohyama Y., Ikari T., Onimaru M., Akimoto N., Jogo R., Mori Y.
Biological characterization and analysis of metastasis-related genes in cell lines derived from the primary lesion and lymph node metastasis of a squamous cell carcinoma arising in the mandibular gingiva.
Int. J. Oncol. 44:1614-1624(2014)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections JCRB; JCRB0260
RCB; RCB1974
TKG; TKG 0470
Cell line databases/resources Cosmic-CLP; 909708
GDSC; 909708
LINCS_LDP; LCL-1221
Ontologies BTO; BTO:0003981
CLO; CLO_0051568
Biological sample resources BioSample; SAMN03471668
BioSample; SAMN03472049
Chemistry resources ChEMBL-Cells; CHEMBL3308781
ChEMBL-Targets; CHEMBL1075569
Gene expression databases GEO; GSM827230
GEO; GSM850387
GEO; GSM950309
GEO; GSM950310
GEO; GSM950311
GEO; GSM950312
GEO; GSM1670402
Polymorphism and mutation databases Cosmic; 909708
Cosmic; 1042300
Cosmic; 1118787
Cosmic; 1120705
Cosmic; 1571803
Cosmic; 2546833