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Cellosaurus SBC-2 [Human contaminated bladder carcinoma] (CVCL_1677)

Cell line name SBC-2 [Human contaminated bladder carcinoma]
Synonyms SBC2
Accession CVCL_1677
Resource Identification Initiative To cite this cell line use: SBC-2 [Human contaminated bladder carcinoma] (RRID:CVCL_1677)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=10508494; PubMed=20143388). Originally thought to originate from an urinary bladder carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00156.
Doubling time: ~40 hours (DSMZ).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): DSMZ

Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx

PubMed=8230540; DOI=10.1016/S0022-5347(17)35941-4
Bohle A., Thanhauser A., Ulmer A.J., Ernst M., Flad H.-D., Jocham D.
Dissecting the immunobiological effects of Bacillus Calmette-Guerin (BCG) in vitro: evidence of a distinct BCG-activated killer (BAK) cell phenomenon.
J. Urol. 150:1932-1937(1993)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cell line collections DSMZ; ACC-228
Cell line databases/resources CLDB; cl4257
Biological sample resources BioSample; SAMN03151755
BioSample; SAMN03473382
Other Wikidata; Q54952164