Cellosaurus SH-4 (CVCL_1692)

Cell line name SH-4
Synonyms SH4
Accession CVCL_1692
Resource Identification Initiative To cite this cell line use: SH-4 (RRID:CVCL_1692)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Melanoma (NCIt: C3224)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP

Markers:
AmelogeninX
CSF1PO11,12
D13S3179,12
D16S53911,12
D5S81811,12
D7S82013
TH018,9.3
TPOX8,11
vWA16,17
Publications

PubMed=1176156; DOI=10.1007/BF02616335
Seman G., Hunter S.J., Lukeman J.M., Dmochowski L.
Establishment of a cell line (SH-4) from pleural effusion of a patient with melanoma.
In Vitro 11:205-211(1975)

PubMed=327080; DOI=10.1093/jnci/59.1.221
Fogh J., Fogh J.M., Orfeo T.
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Fogh J., Wright W.C., Loveless J.D.
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; CRL-7724
BCRJ; 0337
Cell line databases/resources CCLE; SH4_SKIN
Cosmic-CLP; 909713
GDSC; 909713
IGRhCellID; SH4
LINCS_LDP; LCL-1280
Ontologies CLO; CLO_0009006
Biological sample resources BioSample; SAMN03471142
Chemistry resources ChEMBL-Cells; CHEMBL3308177
ChEMBL-Targets; CHEMBL2366309
Gene expression databases GEO; GSM887568
GEO; GSM888651
GEO; GSM1670420
Polymorphism and mutation databases Cosmic; 687440
Cosmic; 909713
Cosmic; 2159447