AC   CVCL_1713
SY   SupB8
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-3610
DR   Cell_Model_Passport; SIDM01177
DR   Cosmic; 910209
DR   Cosmic-CLP; 910209
DR   DepMap; ACH-002308
DR   GDSC; 910209
DR   GEO; GSM1670491
DR   IARC_TP53; 27248
DR   PharmacoDB; SUPB8_1519_2019
DR   Wikidata; Q54970874
RX   PubMed=2541219;
RX   PubMed=20164919;
RX   PubMed=27397505;
RX   PubMed=30894373;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Part of: COSMIC cell lines project.
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Heterozygous for SMARCA4 p.Arg1192Cys (c.3574C>T) (CCLE; Cosmic-CLP).
CC   Sequence variation: Homozygous for TP53 p.Gly245Ser (c.733G>A) (CCLE).
CC   Omics: Deep exome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis.
CC   Genome ancestry: African=0.05%; Native American=0%; East Asian, North=0.63%; East Asian, South=0.05%; South Asian=1.61%; European, North=69.66%; European, South=28% (PubMed=30894373).
CC   Derived from sampling site: Bone marrow.
ST   Source(s): Cosmic-CLP
ST   Amelogenin: X
ST   CSF1PO: 11,13
ST   D13S317: 12
ST   D16S539: 11,12
ST   D5S818: 12,13
ST   D7S820: 9,12
ST   TH01: 9,9.3
ST   TPOX: 8,11
ST   vWA: 15,17
DI   NCIt; C8644; B acute lymphoblastic leukemia
DI   ORDO; Orphanet_99860; Precursor B-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 12-03-20; Version: 21
RX   PubMed=2541219; DOI=10.1084/jem.169.5.1557;
RA   Wright A., Lee J.E., Link M.P., Smith S.D., Carroll W.L., Levy R.,
RA   Clayberger C., Krensky A.M.;
RT   "Cytotoxic T lymphocytes specific for self tumor immunoglobulin
RT   express T cell receptor delta chain.";
RL   J. Exp. Med. 169:1557-1564(1989).
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017;
RA   Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P.,
RA   Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H.,
RA   Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H.,
RA   Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X.,
RA   Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M.,
RA   Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M.,
RA   Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A.,
RA   Saez-Rodriguez J., McDermott U., Garnett M.J.;
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).