Cellosaurus SW1271 (CVCL_1716)

Cell line name SW1271
Synonyms SW-1271; SW 1271
Accession CVCL_1716
Resource Identification Initiative To cite this cell line use: SW1271 (RRID:CVCL_1716)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: RAS genetic alteration cell panel (ATCC TCP-1031).
From: Scott and White Clinic; Temple; Texas; USA.
Microsatellite instability: Stable (MSS) (Sanger).
Sequence variation: Homozygous for NRAS p.Gln61Arg (ATCC).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Small cell lung carcinoma (NCIt: C4917)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP; PubMed=25877200

Markers:
AmelogeninX
CSF1PO11
D13S31713
D16S53911,12
D18S5114
D21S1129,31.2
D3S135815
D5S81812
D7S8209,12
D8S117913,16
FGA20
Penta D10,12
Penta E5,12
TH017,8
TPOX8
vWA17,20
Publications

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; CRL-2177
Cell line databases/resources CCLE; SW1271_LUNG
Cosmic-CLP; 1299062
GDSC; 1299062
LINCS_LDP; LCL-1824
Ontologies CLO; CLO_0009184
Biological sample resources BioSample; SAMN03472877
Gene expression databases GEO; GSM169452
GEO; GSM887665
GEO; GSM888757
GEO; GSM986181
GEO; GSM1670497
Polymorphism and mutation databases Cosmic; 701079
Cosmic; 929966
Cosmic; 932919
Cosmic; 1925844