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Cellosaurus TC-YIK (CVCL_1737)

Cell line name TC-YIK
Synonyms TCYIK
Accession CVCL_1737
Resource Identification Initiative To cite this cell line use: TC-YIK (RRID:CVCL_1737)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Characteristics: Established from the YIK-1 xenograft which was obtained by mutliple serial transplantation of the original tumor in nude mice.
Doubling time: ~21.6 hours, at 119th passage (PubMed=1849445).
Microsatellite instability: Stable (MSS) (Sanger).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Disease Cervical small cell carcinoma (NCIt: C7982)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 31Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB


PubMed=1849445; DOI=10.1002/1097-0142(19910501)67:9<2327::AID-CNCR2820670919>3.0.CO;2-F
Ichimura H., Yamasaki M., Tamura I., Katsumoto T., Sawada M., Kurimura O., Furuyama J.-I., Kurimura T.
Establishment and characterization of a new cell line TC-YIK originating from argyrophil small cell carcinoma of the uterine cervix integrating HPV16 DNA.
Cancer 67:2327-2332(1991)

PubMed=10391092; DOI=10.1111/j.1349-7006.1999.tb00779.x
Ichimura H., Sakashita N., Iida T., Chisaka T., Yasuda H., Kita M., Yuasa S., Imanishi J.
Differentiation of a cell line of human cervical argyrophil small cell carcinoma to macrophage lineage cells.
Jpn. J. Cancer Res. 90:523-529(1999)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cell line collections RCB; RCB0443
Cell line databases/resources CCLE; TCYIK_CERVIX
Cosmic-CLP; 946357
GDSC; 946357
Ontologies CLO; CLO_0050913
Biological sample resources BioSample; SAMN03472316
Chemistry resources ChEMBL-Cells; CHEMBL3308250
ChEMBL-Targets; CHEMBL2366324
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670527
Other Wikidata; Q54971829
Polymorphism and mutation databases Cosmic; 946357
Cosmic; 1995659