ID   TE 159.T
AC   CVCL_1743
SY   TE-159-T; TE159T
DR   CLO; CLO_0009292
DR   ArrayExpress; E-MTAB-2770
DR   ATCC; CRL-7752
DR   BioSample; SAMN03471147
DR   BioSample; SAMN10988169
DR   CCLE; TE159T_FIBROBLAST
DR   Cosmic; 686755
DR   DepMap; ACH-000175
DR   IARC_TP53; 30179
DR   LiGeA; CCLE_329
DR   PharmacoDB; TE159_T_1572_2019
DR   Progenetix; CVCL_1743
DR   Wikidata; Q54971953
RX   PubMed=12068308;
RX   PubMed=30894373;
RX   PubMed=31068700;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=12068308).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg175Leu (c.524G>T); ClinVar=VCV000182963; Zygosity=Unspecified (CCLE).
CC   Omics: Deep exome analysis.
CC   Omics: Deep RNAseq analysis.
CC   Genome ancestry: African=1.8%; Native American=21.64%; East Asian, North=2.4%; East Asian, South=0%; South Asian=1.76%; European, North=45.27%; European, South=27.14% (PubMed=30894373).
ST   Source(s): ATCC
ST   Amelogenin: X,Y
ST   CSF1PO: 12,13
ST   D13S317: 12,14
ST   D16S539: 9,11
ST   D5S818: 9,11
ST   D7S820: 10,11
ST   TH01: 6,9.3
ST   TPOX: 8,11
ST   vWA: 17
DI   NCIt; C3359; Rhabdomyosarcoma
DI   ORDO; Orphanet_780; Rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens
SX   Male
AG   6Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 20-05-21; Version: 18
//
RX   PubMed=12068308; DOI=10.1038/nature00766;
RA   Davies H., Bignell G.R., Cox C., Stephens P.J., Edkins S., Clegg S.,
RA   Teague J.W., Woffendin H., Garnett M.J., Bottomley W., Davis N.,
RA   Dicks E., Ewing R., Floyd Y., Gray K., Hall S., Hawes R., Hughes J.,
RA   Kosmidou V., Menzies A., Mould C., Parker A., Stevens C., Watt S.,
RA   Hooper S., Wilson R., Jayatilake H., Gusterson B.A., Cooper C.,
RA   Shipley J.M., Hargrave D., Pritchard-Jones K., Maitland N.J.,
RA   Chenevix-Trench G., Riggins G.J., Bigner D.D., Palmieri G., Cossu A.,
RA   Flanagan A.M., Nicholson A., Ho J.W.C., Leung S.Y., Yuen S.T.,
RA   Weber B.L., Seigler H.F., Darrow T.L., Paterson H.F., Marais R.,
RA   Marshall C.J., Wooster R., Stratton M.R., Futreal P.A.;
RT   "Mutations of the BRAF gene in human cancer.";
RL   Nature 417:949-954(2002).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//