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Cellosaurus TE-12 (CVCL_1762)

[Text version]

Cell line name TE-12
Synonyms TE12
Accession CVCL_1762
Resource Identification Initiative To cite this cell line use: TE-12 (RRID:CVCL_1762)
Comments Problematic cell line: Contaminated. TE-2, TE-3, TE-7, TE-12 and TE-13 have been shown to be identical (PubMed=17804709; PubMed=20143388).
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00273.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Discontinued: TKG; TKG 0263; probable.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.13
East Asian, North76.19
East Asian, South22.61
South Asian0.51
European, North0.56
European, South0
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_4455 ! TE-2
CVCL_9971 ! TE-3
CVCL_9972 ! TE-7
CVCL_4463 ! TE-13
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO11
D5S81811
D7S82010,13
D13S31712
D16S5399,10
TH019
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Publications

PubMed=8509434; DOI=10.1007/BF01215923
Nishihira T., Hashimoto Y., Katayama M., Mori S., Kuroki T.
Molecular and cellular features of esophageal cancer cells.
J. Cancer Res. Clin. Oncol. 119:441-449(1993)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=17804709; DOI=10.1158/0008-5472.CAN-07-2064
Boonstra J.J., van der Velden A.W., Beerens E.C., van Marion R., Morita-Fujimura Y., Matsui Y., Nishihira T., Tselepis C., Hainaut P., Lowe A.W., Beverloo B.H., van Dekken H., Tilanus H.W., Dinjens W.N.M.
Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7.
Cancer Res. 67:7996-8001(2007)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections TKG; TKG 0263
Cell line databases/resources CCLE; TE12_OESOPHAGUS
Cell_Model_Passport; SIDM00023
Cosmic-CLP; 946356
DepMap; ACH-002311
GDSC; 946356
LINCS_LDP; LCL-1567
Biological sample resources BioSample; SAMN03151963
Chemistry resources ChEMBL-Cells; CHEMBL3308220
ChEMBL-Targets; CHEMBL2366278
PharmacoDB; TE12_1578_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1374958
GEO; GSM1670531
Other Wikidata; Q54972010
Polymorphism and mutation databases Cosmic; 735790
Cosmic; 801329
Cosmic; 923181
Cosmic; 926108
Cosmic; 946356
Cosmic; 947600
Cosmic; 1043234
Cosmic; 1123329
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number23