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Cellosaurus TGBC1TKB (CVCL_1769)

[Text version]

Cell line name TGBC1TKB
Synonyms TGBC-1-TKB; TGBC-1TKB; TGBC1-TKB; TGBC-1
Accession CVCL_1769
Resource Identification Initiative To cite this cell line use: TGBC1TKB (RRID:CVCL_1769)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: 41 hours (PubMed=9824643).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.16
East Asian, North75.35
East Asian, South24.48
South Asian0
European, North0
European, South0
Disease Undifferentiated gallbladder carcinoma (NCIt: C9167)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_3339 ! TGBC2TKB
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB

Markers:
AmelogeninX
CSF1PO14
D5S81811
D7S8209,13
D13S3178,11
D16S5399,11
TH019
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=21533411; DOI=10.3892/ijo.10.3.545
Moon Y., Dahlberg W., Yu Y., Ohno T., Todoroki T., Little J.
Radiosensitivity of human biliary tract cancer cell lines in vitro.
Int. J. Oncol. 10:545-551(1997)

PubMed=9824643; DOI=10.3892/ijo.13.6.1269
Koike N., Todoroki T., Kawamoto T., Yoshida S., Kashiwagi H., Fukao K., Ohno T., Watanabe T.
The invasion potentials of human biliary tract carcinoma cell lines: correlation between invasiveness and morphologic characteristics.
Int. J. Oncol. 13:1269-1274(1998)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=21451941; DOI=10.1007/s00534-011-0376-7
Sato J., Kimura T., Saito T., Anazawa T., Kenjo A., Sato Y., Tsuchiya T., Gotoh M.
Gene expression analysis for predicting gemcitabine resistance in human cholangiocarcinoma.
J. Hepatobiliary Pancreat. Sci. 18:700-711(2011)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections RCB; RCB1129
Cell line databases/resources CCLE; TGBC1TKB_BILIARY_TRACT
Cell_Model_Passport; SIDM00252
Cosmic-CLP; 909769
GDSC; 909769
LINCS_LDP; LCL-1343
Ontologies CLO; CLO_0050019
Biological sample resources BioSample; SAMN03472156
Chemistry resources ChEMBL-Cells; CHEMBL3308852
ChEMBL-Targets; CHEMBL2366089
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670540
Other Wikidata; Q54972238
Polymorphism and mutation databases Cosmic; 909769
Entry history
Entry creation04-Apr-2012
Last entry updated24-May-2019
Version number24