Cellosaurus VMRC-LCP (CVCL_1788)

Cell line name VMRC-LCP
Synonyms VMRCLCP; Patton; Virginia Mason Research Center-Lung Cancer P
Accession CVCL_1788
Resource Identification Initiative To cite this cell line use: VMRC-LCP (RRID:CVCL_1788)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
From: Bean M.A.; Virginia Mason Research Center; Seattle; USA.
Doubling time: ~79 hours (lot 11132014), 93 hours (lot 082994) (JCRB).
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Misspelling: VMR-LCP; In Cosmic 889101.
Disease Squamous cell lung carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO10
D16S53912
D5S81813
D7S82010,12
TH017
TPOX8
vWA18,20
Publications

PubMed=4005855
Kyoizumi S., Akiyama M., Kouno N., Kobuke K., Hakoda M., Jones S.L., Yamakido M.
Monoclonal antibodies to human squamous cell carcinoma of the lung and their application to tumor diagnosis.
Cancer Res. 45:3274-3281(1985)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=14581340
Yokoi S., Yasui K., Iizasa T., Imoto I., Fujisawa T., Inazawa J.
TERC identified as a probable target within the 3q26 amplicon that is detected frequently in non-small cell lung cancers.
Clin. Cancer Res. 9:4705-4713(2003)

PubMed=15185009; DOI=10.1007/s00262-004-0533-9
Yamaji H., Iizasa T., Koh E., Suzuki M., Otsuji M., Chang H., Motohashi S., Yokoi S., Hiroshima K., Tagawa M., Nakayama T., Fujisawa T.
Correlation between interleukin 6 production and tumor proliferation in non-small cell lung cancer.
Cancer Immunol. Immunother. 53:786-792(2004)

PubMed=15746151; DOI=10.1093/hmg/ddi092
Izumi H., Inoue J., Yokoi S., Hosoda H., Shibata T., Sunamori M., Hirohashi S., Inazawa J., Imoto I.
Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers.
Hum. Mol. Genet. 14:997-1007(2005)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=24002593; DOI=10.1038/bjc.2013.452
Wu D., Pang Y., Wilkerson M.D., Wang D., Hammerman P.S., Liu J.S.
Gene-expression data integration to squamous cell lung cancer subtypes reveals drug sensitivity.
Br. J. Cancer 109:1599-1608(2013)

Cross-references
Cell line collections JCRB; JCRB0103
Cell line databases/resources CCLE; VMRCLCP_LUNG
CGH-DB; 193-1
CGH-DB; 9177-4
LINCS_LDP; LCL-1594
Biological sample resources BioSample; SAMN03470791
Chemistry resources ChEMBL-Cells; CHEMBL3308808
ChEMBL-Targets; CHEMBL1075608
Gene expression databases GEO; GSM827200
GEO; GSM1374986
Polymorphism and mutation databases Cosmic; 889101
Cosmic; 930300
Cosmic; 1066175