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Cellosaurus WERI-Rb-1 (CVCL_1792)

[Text version]

Cell line name WERI-Rb-1
Synonyms WERI-RB-1; WERI-Rb 1; WERI-Rb1; WERI-RB1; WERI Rb-1; WERIRb1; WERI; Wills Eye Research Institute-Retinoblastoma-1
Accession CVCL_1792
Secondary accession CVCL_2757
Resource Identification Initiative To cite this cell line use: WERI-Rb-1 (RRID:CVCL_1792)
Comments Part of: ENCODE project common cell types; tier 3.
Doubling time: 96 hours (PubMed=844036); ~49 hours (DSMZ).
Omics: H3K4me3 ChIP-seq epigenome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Retinoblastoma (NCIt: C7541)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 1Y
Category Cancer cell line
STR profile Source(s): ATCC; DSMZ; JCRB; RCB; TKG

Markers:
AmelogeninX
CSF1PO10,12,13 (ATCC; DSMZ; RCB)
11,12 (JCRB)
10 (TKG)
D5S81811,12
D7S82010,13 (ATCC; DSMZ; RCB; TKG)
10,12,13 (JCRB)
D13S31714
D16S53913
TH019.3
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Web pages http://genome.ucsc.edu/ENCODE/protocols/cell/human/WERI-Rb-1_Stam_protocol.pdf
http://www.cellresource.cn/fdetail.aspx?id=1593
Publications

PubMed=844036
McFall R.C., Sery T.W., Makadon M.
Characterization of a new continuous cell line derived from a human retinoblastoma.
Cancer Res. 37:1003-1010(1977)

PubMed=6351622; DOI=10.1016/S0002-9394(14)77822-5
Ohashi Y., Sasabe T., Nishida T., Nishi Y., Higashi H.
Hanganutziu-Deicher heterophile antigen in human retinoblastoma cells.
Am. J. Ophthalmol. 96:321-325(1983)

DOI=10.5795/jjscc.24.451
Tsumuraya M., Nakajima T., Terasaki T., Kodama T., Shimosato Y., Higuchi H., Uei Y.
Analysis of LDH isoenzyme patterns in cell lines of the small cell carcinoma (lung) and retinoblastoma.
Nihon Rinsho Saibo Gakkai Zasshi 24:451-456(1985)

PubMed=2751270
Chan H.S.L., Canton M.D., Gallie B.L.
Chemosensitivity and multidrug resistance to antineoplastic drugs in retinoblastoma cell lines.
Anticancer Res. 9:469-474(1989)

PubMed=1682862; DOI=10.1016/S0161-6420(91)32134-1
Chan H.S.L., Thorner P.S., Haddad G., Gallie B.L.
Multidrug-resistant phenotype in retinoblastoma correlates with P-glycoprotein expression.
Ophthalmology 98:1425-1431(1991)

PubMed=7689221; DOI=10.1073/pnas.90.16.7578
Godbout R., Squire J.A.
Amplification of a DEAD box protein gene in retinoblastoma cell lines.
Proc. Natl. Acad. Sci. U.S.A. 90:7578-7582(1993)

PubMed=7499444; DOI=10.1007/BF01213319
Inomata M., Saijo N., Kawashima K., Kaneko A., Fujiwara Y., Kunikane H., Tanaka Y.
Induction of apoptosis in cultured retinoblastoma cells by the protein phosphatase inhibitor, okadaic acid.
J. Cancer Res. Clin. Oncol. 121:729-738(1995)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=28713896; DOI=10.3892/ijmm.2017.3058
Liu Y., Fan Z.-F., Li K., Deng F., Xiong Y.-F., Liang M.-X., Ge J.
An optimized gene transfection system in WERI-Rb1 cells.
Int. J. Mol. Med. 40:801-813(2017)

Cross-references
Cell line collections AddexBio; C0029002/4899
ATCC; HTB-169
DSMZ; ACC-90
ECACC; 06070602
IZSLER; BS TCL 231
JCRB; JCRB3028
JCRB; KURB2683
RCB; RCB2146
TKG; TKG 0601
Cell line databases/resources CLDB; cl4695
CCRID; 3131C0001001200012
Cell_Model_Passport; SIDM01414
DepMap; ACH-001421
IGRhCellID; WERIRb1
Lonza; 1147
Ontologies CLO; CLO_0009583
CLO; CLO_0009584
CLO; CLO_0051563
EFO; EFO_0005715
Biological sample resources BioSample; SAMN03472730
ENCODE; ENCBS087YAE
ENCODE; ENCBS270AAA
ENCODE; ENCBS282DQM
ENCODE; ENCBS283KOW
ENCODE; ENCBS283WND
ENCODE; ENCBS679NMZ
Gene expression databases ArrayExpress; E-MTAB-783
GEO; GSM824870
GEO; GSM945263
GEO; GSM945318
Other Wikidata; Q54993776
Polymorphism and mutation databases Cosmic; 688119
Cosmic; 909782
Entry history
Entry creation04-Apr-2012
Last entry updated19-Dec-2019
Version number24