Cellosaurus WSU-NHL (CVCL_1793)

Cell line name WSU-NHL
Synonyms WSU-NHL-1; WSUNHL
Accession CVCL_1793
Resource Identification Initiative To cite this cell line use: WSU-NHL (RRID:CVCL_1793)
Comments Part of: MD Anderson Cell Lines Project.
Doubling time: ~45 hours (DSMZ).
Microsatellite instability: Instable (MSI-high) (Sanger).
Omics: Array-based CGH.
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: miRNA expression profiling.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Discontinued: Asterand Bioscience; Catalog number WSU-NHL.
Derived from sampling site: Pleural effusion.
Disease Follicular lymphoma (NCIt: C3209)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,11 (Cosmic-CLP; DSMZ)
11,13 (PubMed=25877200)
D13S3178,11 (Cosmic-CLP; DSMZ)
8,10,11 (PubMed=25877200)
D16S53911,12 (Cosmic-CLP; DSMZ)
10,11,12 (PubMed=25877200)
D18S5115
D19S43313,14,15,15.2
D21S1126,30,31,31.2,32.2
D2S133817,23
D3S135814,15
D5S81811,12 (Cosmic-CLP; DSMZ)
10,11,12 (PubMed=25877200)
D7S82010,12
D8S11799,12,13,14
FGA19,20
Penta D9,10,14
Penta E5,11,12,13
TH016,9 (DSMZ)
9 (Cosmic-CLP; PubMed=25877200)
TPOX9,10 (Cosmic-CLP; DSMZ)
8,9,10,11 (PubMed=25877200)
vWA16 (Cosmic-CLP; DSMZ)
16,17,19 (PubMed=25877200)
Web pages http://www.prnewswire.com/news-releases/asterand-introduces-nine-ways-to-accelerate-cancer-research-55450592.html
http://tcpaportal.org/mclp/
Publications

PubMed=3143865; DOI=10.1016/0145-2126(88)90037-9
Mohamed A.N., Al-Katib A.
Establishment and characterization of a human lymphoma cell line (WSU-NHL) with 14;18 translocation.
Leuk. Res. 12:833-843(1988)

PubMed=7849311
Stranks G., Height S.E., Mitchell P., Jadayel D., Yuille M.A., De Lord C., Clutterbuck R.D., Treleaven J.G., Powles R.L., Nacheva E., Oscier D.G., Karpas A., Lenoir G.M., Smith S.D., Millar J.L., Catovsky D., Dyer M.J.S.
Deletions and rearrangement of CDKN2 in lymphoid malignancy.
Blood 85:893-901(1995)

PubMed=19278952; DOI=10.1182/blood-2009-01-202028
Li C., Kim S.-W., Rai D., Bolla A.R., Adhvaryu S., Kinney M.C., Robetorye R.S., Aguiar R.C.T.
Copy number abnormalities, MYC activity, and the genetic fingerprint of normal B cells mechanistically define the microRNA profile of diffuse large B-cell lymphoma.
Blood 113:6681-6690(2009)

PubMed=23292937; DOI=10.1073/pnas.1205299110
Zhang J., Grubor V., Love C.L., Banerjee A., Richards K.L., Mieczkowski P.A., Dunphy C., Choi W., Au W.Y., Srivastava G., Lugar P.L., Rizzieri D.A., Lagoo A.S., Bernal-Mizrachi L., Mann K.P., Flowers C., Naresh K., Evens A., Gordon L.I., Czader M., Gill J.I., Hsi E.D., Liu Q., Fan A., Walsh K., Jima D., Smith L.L., Johnson A.J., Byrd J.C., Luftig M.A., Ni T., Zhu J., Chadburn A., Levy S., Dunson D., Dave S.S.
Genetic heterogeneity of diffuse large B-cell lymphoma.
Proc. Natl. Acad. Sci. U.S.A. 110:1398-1403(2013)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections ATCC; CRL-11584 - Discontinued
DSMZ; ACC-58
Cell line databases/resources CLDB; cl4734
Cosmic-CLP; 909785
GDSC; 909785
LINCS_LDP; LCL-1955
Ontologies CLO; CLO_0009636
EFO; EFO_0006777
Biological sample resources BioSample; SAMN03470898
BioSample; SAMN03473486
Chemistry resources ChEMBL-Cells; CHEMBL3308281
ChEMBL-Targets; CHEMBL2366193
Gene expression databases GEO; GSM380153
GEO; GSM552470
GEO; GSM1374992
GEO; GSM1670583
Polymorphism and mutation databases Cosmic; 798674
Cosmic; 909785
Cosmic; 994177
Cosmic; 1086348
Cosmic; 1945197
Cosmic; 2276344