Cell line name | ALL-SIL | ||||||||||||||||||
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Synonyms | ALLSIL; SIL-ALL; Sil-ALL | ||||||||||||||||||
Accession | CVCL_1805 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: ALL-SIL (RRID:CVCL_1805) | ||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Doubling time: 64 hours (PubMed=17117183); ~48 hours (DSMZ). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: Transcriptome analysis. Misspelling: AL:L-SIL; In Cosmic 913404. Derived from sampling site: Peripheral blood. | ||||||||||||||||||
Sequence variations | Gene fusion; NUP214-ABL1 (DSMZ).Heterozygous for NOTCH1 p.Leu1574Pro (c.4721T>C) (PubMed=15472075).Heterozygous for NOTCH1 p.Pro2474fs*4 (c.7418_7419insGG) (PubMed=15472075). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Sex of cell | Male | ||||||||||||||||||
Age at sampling | 17Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP; DSMZ Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | https://humantallcelllines.wordpress.com/comprehensivetable/all-sil/ | ||||||||||||||||||
Publications | PubMed=8127147 PubMed=8641406; DOI=10.1111/j.1600-0609.1996.tb00721.x PubMed=10071127; DOI=10.1016/S0145-2126(98)00146-5 DOI=10.1016/B978-0-12-221970-2.50457-5 PubMed=14504097; DOI=10.1182/blood-2003-02-0418 PubMed=15472075; DOI=10.1126/science.1102160 PubMed=17117183; DOI=10.1038/sj.bjc.6603447 PubMed=22675565; DOI=10.1371/journal.pone.0038463 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30285677; DOI=10.1186/s12885-018-4840-5 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | DSMZ; ACC-511 | ||||||||||||||||||
Cell line databases/resources | CCLE; ALLSIL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cell_Model_Passport; SIDM00994 Cosmic-CLP; 1295740 DepMap; ACH-000105 LINCS_LDP; LCL-2059 | ||||||||||||||||||
Ontologies | BTO; BTO:0005360 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03473514
BioSample; SAMN10988449 | ||||||||||||||||||
Chemistry resources | GDSC; 1295740
PharmacoDB; ALLSIL_59_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610 GEO; GSM1669597 | ||||||||||||||||||
Other | Wikidata; Q54749231 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 721715
Cosmic; 913404 Cosmic; 933537 Cosmic; 996306 Cosmic; 998724 Cosmic; 1037687 Cosmic; 1115585 Cosmic; 1175126 Cosmic; 1224372 Cosmic; 1330498 Cosmic; 1524789 Cosmic; 1641391 Cosmic; 1664519 Cosmic; 1760517 Cosmic; 2165718 Cosmic; 2602907 LiGeA; CCLE_156 Progenetix; CVCL_1805 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 12-Jan-2021 | ||||||||||||||||||
Version number | 28 |