Cellosaurus CAL-78 (CVCL_1809)

Cell line name CAL-78
Synonyms CAL 78; CAL78
Accession CVCL_1809
Resource Identification Initiative To cite this cell line use: CAL-78 (RRID:CVCL_1809)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 60 hours, at 15th passage (PubMed=21590123); ~240 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Chondrosarcoma (NCIt: C2946)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ

Markers:
AmelogeninX
CSF1PO12
D13S3178,12
D16S5398,11
D5S81811,12
D7S82011
TH016
TPOX8
vWA16
Publications

PubMed=21590123; DOI=10.3892/or.4.4.697
Mazeau C., Gioanni J., Ettore F., Farges M.-F., Stora de Novion H., Schneider M.
Establishment and characterization of a new cell line derived from a human chondrosarcoma: CAL 78.
Oncol. Rep. 4:697-700(1997)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-449
Cell line databases/resources CCLE; CAL78_BONE
Cosmic-CLP; 1290765
GDSC; 1290765
LINCS_LDP; LCL-1457
Ontologies CLO; CLO_0002189
Biological sample resources BioSample; SAMN03473549
Gene expression databases GEO; GSM886912
GEO; GSM887978
GEO; GSM1669656
Polymorphism and mutation databases Cosmic; 1995359