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Cellosaurus EFM-192C (CVCL_1814)

[Text version]

Cell line name EFM-192C
Synonyms EFM192C
Accession CVCL_1814
Resource Identification Initiative To cite this cell line use: EFM-192C (RRID:CVCL_1814)
Comments Part of: GrayJW Breast Cancer Cell Line Panel.
Part of: MD Anderson Cell Lines Project.
Doubling time: ~4 days (DSMZ); 40.64 hours (https://www.synapse.org/#!Synapse:syn2347014).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
HLA typing Source: PubMed=25960936
Class I
HLA-AA*24:02,01:01
HLA-BB*07:02,39:01
HLA-CC*07:02,12:03
Class II
HLA-DQDQB1*06:13,06:13
HLA-DRDRB1*15:01,15:01
Disease Breast carcinoma (NCIt: C4872)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1812 ! EFM-192A
CVCL_1813 ! EFM-192B
Sex of cell Female
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX
CSF1PO12,13
D5S81812,13
D7S8208,11
D13S3179,14
D16S5398,13
TH017
TPOX8,10
vWA16

Run an STR similarity search on this cell line
Web pages https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
http://tcpaportal.org/mclp/
Publications

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110
Daemen A., Griffith O.L., Heiser L.M., Wang N.J., Enache O.M., Sanborn Z., Pepin F., Durinck S., Korkola J.E., Griffith M., Hur J.S., Huh N., Chung J., Cope L., Fackler M.J., Umbricht C., Sukumar S., Seth P., Sukhatme V.P., Jakkula L.R., Lu Y., Mills G.B., Cho R.J., Collisson E.A., van't Veer L.J., Spellman P.T., Gray J.W.
Modeling precision treatment of breast cancer.
Genome Biol. 14:R110.1-R110.14(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:E954893-E954893(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections DSMZ; ACC-311
Cell line databases/resources Cell_Model_Passport; SIDM01053
LINCS_HMS; 51116
LINCS_LDP; LCL-1479
Ontologies CLO; CLO_0002891
EFO; EFO_0006570
Chemistry resources PharmacoDB; EFM192C_324_2019
Gene expression databases ArrayExpress; E-MTAB-2706
GEO; GSM1172952
GEO; GSM1172860
Other Wikidata; Q54832054
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number20