Home  |  Contact

Cellosaurus HPB-ALL (CVCL_1820)

Cell line name HPB-ALL
Synonyms HPB/ALL; HPBALL; FCCH1018
Accession CVCL_1820
Resource Identification Initiative To cite this cell line use: HPB-ALL (RRID:CVCL_1820)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~50 hours (DSMZ).
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Sequence variations TP53 p.Cys124Ter (c.372C>A) (PubMed=16142349).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_7959 (HPB-MLT)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
STR profile Source(s): DSMZ; RCB; TKG

Markers:
AmelogeninX,Y
CSF1PO10,11
D13S3178,10
D16S5399,11
D5S81811
D7S82011
TH017,9
TPOX8,12
vWA18,20
Web pages http://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-55.html
Publications

PubMed=203546; DOI=10.1002/ijc.2910210207
Morikawa S., Tatsumi E., Baba M., Harada T., Yasuhira K.
Two E-rosette-forming lymphoid cell lines.
Int. J. Cancer 21:166-170(1978)

PubMed=6582512; DOI=10.1073/pnas.81.2.568
Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)

PubMed=1373528
Duan D.-S., Smith W., Sadee W., Cowan M.J.
Characterization of three T-lymphoid cell lines with distinct sensitivities to deoxyadenosine plus deoxycoformycin.
Thymus 19:1-11(1992)

PubMed=8127147
Heyman M., Grander D., Brondum-Nielsen K., Cederblad B., Liu Y., Xu B., Einhorn S.
Interferon system defects in malignant T-cells.
Leukemia 8:425-434(1994)

PubMed=8641406; DOI=10.1111/j.1600-0609.1996.tb00721.x
Borgonovo Brandter L., Heyman M., Rasool O., Liu Y., Grander D., Einhorn S.
p16INK4/p15INK4B gene inactivation is a frequent event in malignant T-cell lines.
Eur. J. Haematol. 56:313-318(1996)

PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x
Takizawa J., Suzuki R., Kuroda H., Utsunomiya A., Kagami Y., Joh T., Aizawa Y., Ueda R., Seto M.
Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia.
Jpn. J. Cancer Res. 89:712-718(1998)

PubMed=9933131; DOI=10.1016/S0145-2126(98)00133-7
Burger R., Hansen-Hagge T.E., Drexler H.G., Gramatzki M.
Heterogeneity of T-acute lymphoblastic leukemia (T-ALL) cell lines: suggestion for classification by immunophenotype and T-cell receptor studies.
Leuk. Res. 23:19-27(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=16142349; DOI=10.3892/or.14.4.901
Smardova J., Pavlova S., Svitakova M., Grochova D., Ravcukova B.
Analysis of p53 status in human cell lines using a functional assay in yeast: detection of new non-sense p53 mutation in codon 124.
Oncol. Rep. 14:901-907(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=22675565; DOI=10.1371/journal.pone.0038463
Kalender Atak Z., De Keersmaecker K., Gianfelici V., Geerdens E., Vandepoel R., Pauwels D., Porcu M., Lahortiga I., Brys V., Dirks W.G., Quentmeier H., Cloos J., Cuppens H., Uyttebroeck A., Vandenberghe P., Cools J., Aerts S.
High accuracy mutation detection in leukemia on a selected panel of cancer genes.
PLoS ONE 7:E38463-E38463(2012)

Cross-references
Cell line collections DSMZ; ACC-483
NCBI_Iran; C213
RCB; RCB1935
TKG; TKG 0199
Cell line databases/resources CCLE; HPBALL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Lonza; 250
Ontologies BTO; BTO:0001952
CLO; CLO_0003817
CLO; CLO_0050988
Biological sample resources BioSample; SAMN01821632
BioSample; SAMN03473562
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887091
GEO; GSM888162
Other Wikidata; Q54890235
Polymorphism and mutation databases Cosmic; 801726
Cosmic; 913406
Cosmic; 919159
Cosmic; 933550
Cosmic; 998736
Cosmic; 999754
Cosmic; 1037689
Cosmic; 1115583
Cosmic; 1130235
Cosmic; 1151779
Cosmic; 1224373
Cosmic; 1281368
Cosmic; 1330499
Cosmic; 1524796
Cosmic; 1641378
Cosmic; 1664521
Cosmic; 1760522
Cosmic; 2165711
Cosmic; 2602914