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Cellosaurus LAMA-87 (CVCL_1826)

[Text version]
Cell line name LAMA-87
Synonyms Lama-87; LAMA87
Accession CVCL_1826
Resource Identification Initiative To cite this cell line use: LAMA-87 (RRID:CVCL_1826)
Comments Characteristics: Established after subcutaneous transplantation of parent cells into estrone-treated nude mice.
Doubling time: ~50-60 hours (DSMZ=ACC-270).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=10071072).
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys319Ter (c.955A>T); Zygosity=Homozygous (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0388 (LAMA-84)
Sex of cell Female
Age at sampling 29Y
Category Cancer cell line
STR profile Source(s): DSMZ; Millipore

Markers:
AmelogeninX
CSF1PO11,12
D2S133817
D3S135814,17
D5S81811,12
D7S82011
D8S117910,15
D13S31711
D16S53911
D18S5113
D19S43313
D21S1129,31
FGA21,22
Penta D10
Penta E7
TH016,7
TPOX10
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=7996872; DOI=10.1016/0145-2126(94)90102-3
Champelovier P., Valiron O., Jacrot M., Leroux D., Seigneurin D.
Selection and characterization of an erythroeosinophilic subclone (LAMA-87) and an eosinophilic subclone (LAMA-88) from the multipotential cell line LAMA-84.
Leuk. Res. 18:903-918(1994)

PubMed=9257809
Champelovier P., Fixe P., Valiron O., Feige J.-J., Praloran V., Seigneurin D.
Proliferation of LAMA-84 and LAMA-87 cell lines is modulated by autocrine loops involving M-CSF and TGF-beta.
Exp. Hematol. 25:958-965(1997)

PubMed=10071072; DOI=10.1016/s0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

Cross-references
Cell line collections (Providers) DSMZ; ACC-270
Millipore; SCC138
Cell line databases/resources CLO; CLO_0007239
CLDB; cl55
Cell_Model_Passport; SIDM01230
DSMZCellDive; ACC-270
Anatomy/cell type resources BTO; BTO:0004466
Biological sample resources BioSample; SAMN03473337
Encyclopedic resources Wikidata; Q54901915
Polymorphism and mutation databases Cosmic; 787501
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number21