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Cellosaurus MAVER-1 (CVCL_1831)

[Text version]

Cell line name MAVER-1
Synonyms Maver-1; MAVER1; Maver1; MAVER; MAntle cell VERona-1
Accession CVCL_1831
Resource Identification Initiative To cite this cell line use: MAVER-1 (RRID:CVCL_1831)
Comments Part of: Lymphoma Research Foundation Mantle Cell Lymphoma cell bank (LRF MCL cell bank).
Doubling time: 24 hours (PubMed=25315077); ~48 hours (DSMZ).
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Sequence variations Hemizygous for TP53 p.Asp281Glu (c.843C>G) (ClinVar=VCV000376587) (PubMed=16434369).
HLA typing Source: PubMed=25960936
Class I
HLA-AA*68:01,02:01
HLA-BB*55:01,07:02
HLA-CC*03:03,07:02
Class II
HLA-DQDQA1*05:01,02:01
DQB1*03:01,02:01
HLA-DRDRB1*11:01,07:01

Source: PubMed=25688540
Class I
HLA-AA*24,26
HLA-BB*38,44
HLA-CC*05,12
Disease Mantle cell lymphoma (NCIt: C4337)
Mantle cell lymphoma (ORDO: Orphanet_52416)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 82Y
Category Cancer cell line
STR profile Source(s): ATCC; DSMZ

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81812
D7S8208
D13S3178,13
D16S5399,12
TH018,9
TPOX8,12
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=16434369
Zamo A., Ott G., Katzenberger T., Adam P., Parolini C., Scarpa A., Lestani M., Menestrina F., Chilosi M.
Establishment of the MAVER-1 cell line, a model for leukemic and aggressive mantle cell lymphoma.
Haematologica 91:40-47(2006)

PubMed=24362935; DOI=10.1038/nm.3435
Rahal R., Frick M., Romero R., Korn J.M., Kridel R., Chan F.C., Meissner B., Bhang H.-E., Ruddy D., Kauffmann A., Farsidjani A., Derti A., Rakiec D., Naylor T., Pfister E., Kovats S., Kim S., Dietze K., Dorken B., Steidl C., Tzankov A., Hummel M., Monahan J., Morrissey M.P., Fritsch C., Sellers W.R., Cooke V.G., Gascoyne R.D., Lenz G., Stegmeier F.
Pharmacological and genomic profiling identifies NF-kappaB-targeted treatment strategies for mantle cell lymphoma.
Nat. Med. 20:87-92(2014)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:E954893-E954893(2014)

PubMed=25315077; DOI=10.3109/10428194.2014.970548
Fogli L.K., Williams M.E., Connors J.M., Reid Y.A., Brown K., O'Connor O.A.
Development and characterization of a Mantle Cell Lymphoma Cell Bank in the American Type Culture Collection.
Leuk. Lymphoma 56:2114-2122(2015)

PubMed=25688540; DOI=10.1002/cyto.a.22643
Maiga S., Brosseau C., Descamps G., Dousset C., Gomez-Bougie P., Chiron D., Menoret E., Kervoelen C., Vie H., Cesbron A., Moreau-Aubry A., Amiot M., Pellat-Deceunynck C.
A simple flow cytometry-based barcode for routine authentication of multiple myeloma and mantle cell lymphoma cell lines.
Cytometry A 87:285-288(2015)

PubMed=27697772; DOI=10.1182/blood-2016-06-720490
Chiron D., Bellanger C., Papin A., Tessoulin B., Dousset C., Maiga S., Moreau A., Esbelin J., Trichet V., Chen-Kiang S., Moreau P., Touzeau C., Le Gouill S., Amiot M., Pellat-Deceunynck C.
Rational targeted therapies to overcome microenvironment-dependent expansion of mantle cell lymphoma.
Blood 128:2808-2818(2016)

PubMed=29666304; DOI=10.1158/1078-0432.CCR-17-3004
Pham L.V., Huang S.-J., Zhang H., Zhang J., Bell T., Zhou S., Pogue E., Ding Z., Lam L., Westin J., Davis R.E., Young K.H., Medeiros L.J., Ford R.J., Nomie K., Zhang L., Wang M.
Strategic therapeutic targeting to overcome venetoclax resistance in aggressive B-cell lymphomas.
Clin. Cancer Res. 24:3967-3980(2018)

Cross-references
Cell line collections ATCC; CRL-3008
DSMZ; ACC-717
Biological sample resources BioSample; SAMN03471709
Gene expression databases GEO; GSM1044978
GEO; GSM1044979
GEO; GSM1044980
GEO; GSM1044981
GEO; GSM1266781
GEO; GSM1266782
GEO; GSM1266793
GEO; GSM1266794
GEO; GSM1266795
GEO; GSM1266796
GEO; GSM1266797
GEO; GSM1266798
GEO; GSM2322621
Other Wikidata; Q54904067
Polymorphism and mutation databases Cosmic; 2078182
Cosmic; 2088018
IARC_TP53; 24552
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number19