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Cellosaurus OACM5.1 C (CVCL_1842)

[Text version]

Cell line name OACM5.1 C
Synonyms OAC-M5.1 C; OAC-M5.1; OACM5-1; OACM5.1; OACM5_1; OACM51
Accession CVCL_1842
Resource Identification Initiative To cite this cell line use: OACM5.1 C (RRID:CVCL_1842)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: ~48 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Genome sequenced.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.02
East Asian, North0
East Asian, South0
South Asian1.6
European, North72.08
European, South26.29
Disease Esophageal adenocarcinoma (NCIt: C4025)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_JX13 (OACM5 1.C SC1)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; ECACC; PubMed=20075370

Markers:
AmelogeninX
CSF1PO10,13
D3S135816,17
D5S81811,12 (Cosmic-CLP; DSMZ; ECACC)
12 (PubMed=20075370)
D7S8208 (Cosmic-CLP; DSMZ; PubMed=20075370)
8.2 (ECACC)
D8S117913,14
D13S31711,12
D16S53910,11
D18S5116
D21S1128,31
FGA22
Penta D10
Penta E7,14
TH016,9.3
TPOX8
vWA19,20

Run an STR similarity search on this cell line
Publications

PubMed=11407472; DOI=10.1007/s004280000358
de Both N.J., Wijnhoven B.P.L., Sleddens H.F.B.M., Tilanus H.W., Dinjens W.N.M.
Establishment of cell lines from adenocarcinomas of the esophagus and gastric cardia growing in vivo and in vitro.
Virchows Arch. 438:451-456(2001)

PubMed=20075370; DOI=10.1093/jnci/djp499
Boonstra J.J., van Marion R., Beer D.G., Lin L., Chaves P., Ribeiro C., Pereira A.D., Roque L., Darnton S.J., Altorki N.K., Schrump D.S., Klimstra D.S., Tang L.H., Eshleman J.R., Alvarez H., Shimada Y., van Dekken H., Tilanus H.W., Dinjens W.N.M.
Verification and unmasking of widely used human esophageal adenocarcinoma cell lines.
J. Natl. Cancer Inst. 102:271-274(2010)

PubMed=23795680; DOI=10.1111/dote.12095
Boonstra J.J., Tilanus H.W., Dinjens W.N.M.
Translational research on esophageal adenocarcinoma: from cell line to clinic.
Dis. Esophagus 28:90-96(2015)

DOI=10.12688/f1000research.7033.1
Contino G., Eldridge M.D., Secrier M., Bower L., Elliott R.F., Weaver J., Lynch A.G., Edwards P.A.W., Fitzgerald R.C.
Whole-genome sequencing of nine esophageal adenocarcinoma cell lines.
F1000Research 5:1336-1336(2016)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28504813; DOI=10.3892/or.2017.5640
Melsens E., De Vlieghere E., Descamps B., Vanhove C., De Wever O., Ceelen W., Pattyn P.
Improved xenograft efficiency of esophageal adenocarcinoma cell lines through in vivo selection.
Oncol. Rep. 38:71-81(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections DSMZ; ACC-696
ECACC; 11012006
Cell line databases/resources CCLE; OACM51_OESOPHAGUS
Cell_Model_Passport; SIDM00444
Cosmic-CLP; 1503363
DepMap; ACH-001368
GDSC; 1503363
Biological sample resources BioSample; SAMN03473445
Chemistry resources PharmacoDB; OACM51_1176_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670290
Other Wikidata; Q54931676
Polymorphism and mutation databases Cosmic; 1599344
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number21