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Cellosaurus OACP4 C (CVCL_1843)

[Text version]

Cell line name OACP4 C
Synonyms OAC-P4C; OACP4C; OACp4C
Accession CVCL_1843
Resource Identification Initiative To cite this cell line use: OACP4 C (RRID:CVCL_1843)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: ~35-50 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Genome sequenced.
Omics: Transcriptome analysis.
Misspelling: OACP4CE; In PubMed=23795680.
Sequence variations TP53 p.Gln192Ter (c.574C>T) (PubMed=20075370).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.19
Native American0.55
East Asian, North0
East Asian, South1.33
South Asian0.08
European, North66.1
European, South31.76
Disease Esophageal adenocarcinoma (NCIt: C4025)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2249 ! OACM4.1 C
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; ECACC; PubMed=20075370

Markers:
AmelogeninX
CSF1PO11
D3S135818
D5S8189
D7S8209,11
D8S117913
D13S31712
D16S53912
D18S5112,13
D21S1130
FGA20
Penta D12
Penta E20
TH019
TPOX11
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=11407472; DOI=10.1007/s004280000358
de Both N.J., Wijnhoven B.P.L., Sleddens H.F.B.M., Tilanus H.W., Dinjens W.N.M.
Establishment of cell lines from adenocarcinomas of the esophagus and gastric cardia growing in vivo and in vitro.
Virchows Arch. 438:451-456(2001)

PubMed=20075370; DOI=10.1093/jnci/djp499
Boonstra J.J., van Marion R., Beer D.G., Lin L., Chaves P., Ribeiro C., Pereira A.D., Roque L., Darnton S.J., Altorki N.K., Schrump D.S., Klimstra D.S., Tang L.H., Eshleman J.R., Alvarez H., Shimada Y., van Dekken H., Tilanus H.W., Dinjens W.N.M.
Verification and unmasking of widely used human esophageal adenocarcinoma cell lines.
J. Natl. Cancer Inst. 102:271-274(2010)

PubMed=23795680; DOI=10.1111/dote.12095
Boonstra J.J., Tilanus H.W., Dinjens W.N.M.
Translational research on esophageal adenocarcinoma: from cell line to clinic.
Dis. Esophagus 28:90-96(2015)

DOI=10.12688/f1000research.7033.1
Contino G., Eldridge M.D., Secrier M., Bower L., Elliott R.F., Weaver J., Lynch A.G., Edwards P.A.W., Fitzgerald R.C.
Whole-genome sequencing of nine esophageal adenocarcinoma cell lines.
F1000Research 5:1336-1336(2016)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections DSMZ; ACC-704
ECACC; 11012005
Cell line databases/resources CCLE; OACP4C_OESOPHAGUS
Cell_Model_Passport; SIDM00445
Cosmic-CLP; 1503362
DepMap; ACH-002292
GDSC; 1503362
Biological sample resources BioSample; SAMN03473391
Chemistry resources PharmacoDB; OACp4C_1177_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670291
Other Wikidata; Q54931678
Polymorphism and mutation databases Cosmic; 1599345
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number22