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Cellosaurus BC-2 (CVCL_1856)

[Text version]

Cell line name BC-2
Synonyms BC2
Accession CVCL_1856
Resource Identification Initiative To cite this cell line use: BC-2 (RRID:CVCL_1856)
Comments Doubling time: ~50-70 hours (DSMZ).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV).
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Pleural effusion.
Disease Primary effusion lymphoma (NCIt: C6915)
Primary effusion lymphoma (ORDO: Orphanet_48686)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 31Y
Category Cancer cell line
STR profile Source(s): ATCC; DSMZ


Run an STR similarity search on this cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=BC-2

PubMed=7670109; DOI=10.1182/blood.V86.7.2708.2708
Cesarman E., Moore P.S., Rao P.H., Inghirami G., Knowles D.M., Chang Y.
In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi's sarcoma-associated herpesvirus-like (KSHV) DNA sequences.
Blood 86:2708-2714(1995)

Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=15613351; DOI=10.1128/JVI.79.2.1244-1251.2005
Fan W., Bubman D., Chadburn A., Harrington W.J. Jr., Cesarman E., Knowles D.M.
Distinct subsets of primary effusion lymphoma can be identified based on their cellular gene expression profile and viral association.
J. Virol. 79:1244-1251(2005)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=21685375; DOI=10.1182/blood-2010-12-323659
Roy D., Sin S.-H., Damania B., Dittmer D.P.
Tumor suppressor genes FHIT and WWOX are deleted in primary effusion lymphoma (PEL) cell lines.
Blood 118:E32-E39(2011)

Cell line collections ATCC; CRL-2231
Cell line databases/resources IGRhCellID; BC2
Ontologies BTO; BTO:0002721
CLO; CLO_0001889
EFO; EFO_0002045
Biological sample resources BioSample; SAMN03471845
BioSamples; SAMEA365820
BioSamples; SAMEA365831
Chemistry resources GDSC; 1295743
PharmacoDB; BC2_78_2019
Gene expression databases GEO; GSM38794
GEO; GSM38795
GEO; GSM634732
GEO; GSM710418
GEO; GSM710434
Other Wikidata; Q54795187
Polymorphism and mutation databases Cosmic; 1238076
Cosmic; 1515187
Cosmic; 1588557
Entry history
Entry creation04-Apr-2012
Last entry update12-Mar-2020
Version number20