Cellosaurus CCRF-HSB-2 (CVCL_1859)

Cell line name CCRF-HSB-2
Synonyms CCRF HSB-2; CCRF-HSB2; HSB-2; HSB2; H-SB2; HSB; H.S.B.; GM04155
Accession CVCL_1859
Secondary accession CVCL_5938
Resource Identification Initiative To cite this cell line use: CCRF-HSB-2 (RRID:CVCL_1859)
Comments Doubling time: 40 hours (PubMed=17117183); ~25 hours (DSMZ).
Misspelling: CCRF-HBS-2; In NCBI_Iran C530.
Derived from sampling site: Peripheral blood.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_1Y12 (HSB2/GS)
Originate from same individual CVCL_1860 ! CCRF-SB
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ATCC; CLS; DSMZ; ECACC; JCRB; KCLB; RCB

Markers:
AmelogeninX,Y (ATCC; DSMZ; ECACC; JCRB; KCLB; RCB)
X (CLS)
CSF1PO10,12 (ATCC; ECACC; JCRB; KCLB; RCB)
8,12 (CLS)
10,11 (DSMZ)
D13S31710,12
D16S5399,13 (ATCC; ECACC; JCRB; RCB)
9,13,14 (CLS)
9,12 (DSMZ)
D18S519,13,14
D21S1128,29
D3S135815,16
D5S81811,12
D7S82011,12 (ATCC; DSMZ; ECACC; JCRB; KCLB; RCB)
10,14 (CLS)
D8S11799,15
FGA22,23,24 (CLS)
24,25 (KCLB)
Penta D9
Penta E6,13
TH019,10 (ATCC; DSMZ; ECACC; JCRB; RCB)
8,10 (CLS)
9,9.3 (KCLB)
TPOX8
vWA18,19 (ATCC; DSMZ; ECACC; JCRB; KCLB)
18,19,20 (CLS; RCB)
Publications

PubMed=4523807; DOI=10.1007/BF02616012
Lazarus H., Barell E.F., Oppenheim S., Krishan A.
Divergent properties of two human lymphocytic cell lines isolated from a single specimen of peripheral blood.
In Vitro 9:303-310(1974)

PubMed=62390; DOI=10.1111/j.1365-3083.1976.tb03029.x
Yount W.J., Utsinger P.D., Hutt L.M., Buchanan P.D., Korn J.H., Fuller C.R., Logue M., Pagano J.S.
Subpopulations of human lymphoblastoid cell lines. Correlation with the expression of surface receptors and content of Epstein-Barr virus genome.
Scand. J. Immunol. 5:795-810(1976)

PubMed=6600440; DOI=10.1007/BF02617996
Uittenbogaart C.H., Cantor Y., Fahey J.L.
Growth of human malignant lymphoid cell lines in serum-free medium.
In Vitro 19:67-72(1983)

PubMed=6582512; DOI=10.1073/pnas.81.2.568
Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O.
Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984)

PubMed=3495441; DOI=10.1002/eji.1830170503
Kanowith-Klein S., Saxon A., Uittenbogaart C.H.
Constitutive production of B cell differentiation factor-like activity by human T and B cell lines.
Eur. J. Immunol. 17:593-598(1987)

PubMed=8316623; DOI=10.2307/3578190
Evans H.H., Ricanati M., Horng M.-F., Jiang Q., Mencl J., Olive P.
DNA double-strand break rejoining deficiency in TK6 and other human B-lymphoblast cell lines.
Radiat. Res. 134:307-315(1993)

PubMed=8547074; DOI=10.1111/j.1365-2141.1995.tb05302.x
Siebert R., Willers C.P., Schramm A., Fossa A., Dresen I.M.G., Uppenkamp M., Nowrousian M.R., Seeber S., Opalka B.
Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and lymphoblastic leukaemia cell lines.
Br. J. Haematol. 91:350-354(1995)

PubMed=9933131; DOI=10.1016/S0145-2126(98)00133-7
Burger R., Hansen-Hagge T.E., Drexler H.G., Gramatzki M.
Heterogeneity of T-acute lymphoblastic leukemia (T-ALL) cell lines: suggestion for classification by immunophenotype and T-cell receptor studies.
Leuk. Res. 23:19-27(1999)

PubMed=17117183; DOI=10.1038/sj.bjc.6603447
Beesley A.H., Palmer M.-L., Ford J., Weller R.E., Cummings A.J., Freitas J.R., Firth M.J., Perera K.U., de Klerk N.H., Kees U.R.
Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines.
Br. J. Cancer 95:1537-1544(2006)

PubMed=22675565; DOI=10.1371/journal.pone.0038463
Kalender Atak Z., De Keersmaecker K., Gianfelici V., Geerdens E., Vandepoel R., Pauwels D., Porcu M., Lahortiga I., Brys V., Dirks W.G., Quentmeier H., Cloos J., Cuppens H., Uyttebroeck A., Vandenberghe P., Cools J., Aerts S.
High accuracy mutation detection in leukemia on a selected panel of cancer genes.
PLoS ONE 7:E38463-E38463(2012)

Cross-references
Cell line collections ATCC; CCL-120.1
CLS; 300214/p639_HSB
Coriell; GM04155
DSMZ; ACC-435
ECACC; 85112801
IZSLER; BS TCL 185
JCRB; JCRB0031
KCLB; 10120.1
NCBI_Iran; C530
NIH-ARP; 497-277
RCB; RCB0016
Cell line databases/resources CLDB; cl678
LINCS_LDP; LCL-1914
Ontologies BTO; BTO:0005370
CLO; CLO_0002335
CLO; CLO_0004258
CLO; CLO_0016177
CLO; CLO_0050971
Biological sample resources BioSample; SAMN03472334
BioSample; SAMN03472701
BioSample; SAMN03473542
Chemistry resources ChEMBL-Cells; CHEMBL3307642
ChEMBL-Targets; CHEMBL614541
Polymorphism and mutation databases Cosmic; 683532
Cosmic; 801729
Cosmic; 850195
Cosmic; 913416
Cosmic; 922679
Cosmic; 932768
Cosmic; 996307
Cosmic; 998723
Cosmic; 1037688
Cosmic; 1115591
Cosmic; 1175128
Cosmic; 1226856
Cosmic; 1281369
Cosmic; 1330497
Cosmic; 1524797
Cosmic; 1641390
Cosmic; 1760523
Cosmic; 2165712
Cosmic; 2361365
Cosmic; 2458762
Cosmic; 2462861
Cosmic; 2602915