Cellosaurus COLO 677 (CVCL_1862)

Cell line name COLO 677
Synonyms COLO-677; COLO677
Accession CVCL_1862
Resource Identification Initiative To cite this cell line use: COLO 677 (RRID:CVCL_1862)
Comments Problematic cell line: Contaminated. Shown to be a RPMI-8226 derivative (PubMed=20143388).
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Characteristics: Produces IgG lambda.
Doubling time: ~40 hours (DSMZ).
Sequence variation: Heterozygous for EGFR p.Thr751Ile (from parent cell line).
Sequence variation: Heterozygous for KRAS p.Gly12Ala (from parent cell line).
Sequence variation: Homozygous for TP53 p.Glu285Lys (from parent cell line).
Derived from sampling site: Peripheral blood.
Disease Plasma cell myeloma (NCIt: C3242)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0014 (RPMI-8226)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX,Y
CSF1PO12
D13S31711
D16S5399
D5S81811,13
D7S8209,10
TH018
TPOX8,11
vWA16,18
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf
Publications

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections DSMZ; ACC-248
ECACC; 93072109
Cell line databases/resources CLDB; cl837
CLDB; cl838
CCLE; COLO677_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Ontologies CLO; CLO_0002550
Biological sample resources BioSample; SAMN03151910
Gene expression databases GEO; GSM784242
Polymorphism and mutation databases Cosmic; 753542