Cellosaurus MUTZ-5 (CVCL_1873)

Cell line name MUTZ-5
Synonyms Mutz-5; MUTZ5
Accession CVCL_1873
Resource Identification Initiative To cite this cell line use: MUTZ-5 (RRID:CVCL_1873)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~70-100 hours (DOI=10.1007/978-3-642-59358-1_5; DSMZ).
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Disease B acute lymphoblastic leukemia (NCIt: C8644)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L068 ! MUTZ-6
CVCL_L069 ! MUTZ-7
Sex of cell Male
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX
CSF1PO8,9
D13S31710,12
D16S53910
D5S81811
D7S82010
TH017
TPOX8,11
vWA16,17
Publications

PubMed=11516110; DOI=10.1038/sj.leu.2402212
Meyer C., MacLeod R.A.F., Quentmeier H., Janssen J.W.G., Coignet L.J.A., Dyer M.J.S., Drexler H.G.
Establishment of the B cell precursor acute lymphoblastic leukemia cell line MUTZ-5 carrying a (12:13) translocation.
Leukemia 15:1471-1474(2001)

DOI=10.1007/978-3-642-59358-1_5
Meyer C., MacLeod R.A.F., Quentmeier H., Janssen J.W.G., Coignet L.J.A., Drexler H.G.
Establishment of the B-cell precursor-acute lymphoblastic leukemia cell line MUTZ-5 carrying a (12:13) translocation.
(In) Acute leukemias IX. Haematology and blood transfusion, Vol. 41; Hiddemann W., Haferlach T., Unterhalt M., Buechner T., Ritter J. (eds.); pp.15-18; Springer; Berlin (2003)

PubMed=15843827; DOI=10.1038/sj.leu.2403749
Andersson A., Eden P., Lindgren D., Nilsson J., Lassen C., Heldrup J., Fontes M., Borg A., Mitelman F., Johansson B., Hoglund M., Fioretos T.
Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations.
Leukemia 19:1042-1050(2005)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

Cross-references
Cell line collections DSMZ; ACC-490
Cell line databases/resources CCLE; MUTZ5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Biological sample resources BioSample; SAMN03473564
Gene expression databases GEO; GSM887343
GEO; GSM888419
Polymorphism and mutation databases Cosmic; 1130257
Cosmic; 1278371
Cosmic; 1519165
Cosmic; 1524809