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Cellosaurus OCI-Ly18 (CVCL_1880)

[Text version]

Cell line name OCI-Ly18
Synonyms OCI-LY18; OCI-LY-18; OCI-Ly 18; Ly18; LY18
Accession CVCL_1880
Secondary accession CVCL_9551
Resource Identification Initiative To cite this cell line use: OCI-Ly18 (RRID:CVCL_1880)
Comments From: Ontario Cancer Institute (OCI); Toronto; Canada.
Doubling time: ~30-40 hours (DSMZ).
Omics: Array-based CGH.
Omics: CNV analysis.
Omics: miRNA expression profiling.
Omics: Transcriptome analysis.
Misspelling: OCI-LZ18; In BioSample SAMN03473448.
Misspelling: SU-DHL-18; In Cosmic 1295513.
Derived from sampling site: Pleural effusion.
Disease Diffuse large B-cell lymphoma (NCIt: C8851)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): DSMZ


Run an STR similarity search on this cell line
Web pages http://www.innovationbridge.com/uhn/diffuse-large-b-cell-lymphoma-cell-lines?categories=32&communities=5&forums=&organizations=&tags=

PubMed=1311715; DOI=10.1172/JCI115642
Chang H., Messner H.A., Wang X.-H., Yee C., Addy L., Meharchand J., Minden M.D.
A human lymphoma cell line with multiple immunoglobulin rearrangements.
J. Clin. Invest. 89:1014-1020(1992)

PubMed=8574164; DOI=10.3109/10428199509059672
Chang H., Blondal J.A., Benchimol S., Minden M.D., Messner H.A.
p53 mutations, c-myc and bcl-2 rearrangements in human non-Hodgkin's lymphoma cell lines.
Leuk. Lymphoma 19:165-171(1995)

Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=11807979; DOI=10.1002/gcc.10025
Mehra S., Messner H.A., Minden M.D., Chaganti R.S.K.
Molecular cytogenetic characterization of non-Hodgkin lymphoma cell lines.
Genes Chromosomes Cancer 33:225-234(2002)

PubMed=19278952; DOI=10.1182/blood-2009-01-202028
Li C., Kim S.-W., Rai D., Bolla A.R., Adhvaryu S., Kinney M.C., Robetorye R.S., Aguiar R.C.T.
Copy number abnormalities, MYC activity, and the genetic fingerprint of normal B cells mechanistically define the microRNA profile of diffuse large B-cell lymphoma.
Blood 113:6681-6690(2009)

PubMed=26727417; DOI=10.3109/10428194.2015.1108414
Drexler H.G., Eberth S., Nagel S., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for double-hit B-cell lymphomas.
Leuk. Lymphoma 57:1015-1020(2016)

Cell line collections DSMZ; ACC-699
Biological sample resources BioSample; SAMN03473448
Gene expression databases GEO; GSM380131
GEO; GSM552456
GEO; GSM1374785
Other Wikidata; Q54931770
Wikidata; Q54970714
Polymorphism and mutation databases Cosmic; 1295513
Cosmic; 1517651
Cosmic; 1541906
Cosmic; 1636683
Cosmic; 2276334
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number19