Cell line name | ONCO-DG-1 | ||||||||||||||||||
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Synonyms | ONCO-DG 1; ONCO-DG1; ONCODG1 | ||||||||||||||||||
Accession | CVCL_1882 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: ONCO-DG-1 (RRID:CVCL_1882) | ||||||||||||||||||
Comments | Problematic cell line: Contaminated. Shown to be a OVCAR-3 derivative (PubMed=20143388). Originally thought to originate from a 49 year old female patient with a thyroid gland papillary carcinoma. Part of: Cancer Cell Line Encyclopedia (CCLE) project. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00338. Doubling time: ~30 hours (DSMZ). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. | ||||||||||||||||||
Sequence variations | Homozygous for TP53 p.Arg248Gln (c.743G>A) (ClinVar=VCV000012356) (PubMed=14522906). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | High grade ovarian serous adenocarcinoma (NCIt: C105555) Derived from metastatic site: Ascites. | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Hierarchy | Parent: CVCL_0465 (OVCAR-3) | ||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||
Age at sampling | 60Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): DSMZ Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | http://iclac.org/wp-content/uploads/Cross-Contaminations_v10_distribution.xlsx | ||||||||||||||||||
Publications | PubMed=1381131; DOI=10.1007/BF02899670 PubMed=14522906 PubMed=20143388; DOI=10.1002/ijc.25242 PubMed=23839242; DOI=10.1038/ncomms3126 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | DSMZ; ACC-507 | ||||||||||||||||||
Cell line databases/resources | CCLE; ONCODG1_OVARY
Cell_Model_Passport; SIDM00093 DepMap; ACH-000013 | ||||||||||||||||||
Ontologies | BTO; BTO:0004847 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03151879
BioSample; SAMN10988512 | ||||||||||||||||||
Chemistry resources | PharmacoDB; ONCODG1_1200_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-2770 | ||||||||||||||||||
Other | Wikidata; Q54936399 | ||||||||||||||||||
Polymorphism and mutation databases | IARC_TP53; 27010
LiGeA; CCLE_540 Progenetix; CVCL_1882 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 29-Oct-2020 | ||||||||||||||||||
Version number | 25 |