Cellosaurus REC-1 (CVCL_1884)

Cell line name REC-1
Synonyms Rec-1; REC 1; REC1; REC
Accession CVCL_1884
Resource Identification Initiative To cite this cell line use: REC-1 (RRID:CVCL_1884)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: Lymphoma Research Foundation Mantle Cell Lymphoma cell bank (LRF MCL cell bank).
Part of: MD Anderson Cell Lines Project.
Doubling time: 38 hours (PubMed=25315077); ~20-40 hours (DSMZ).
Omics: Deep RNAseq analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Omics: Virome analysis using RNAseq.
Disease Mantle cell lymphoma (NCIt: C4337)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ATCC; DSMZ; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10,12
D13S31710
D16S53911
D18S5114,16
D21S1128,29
D3S135815,16
D5S81812,13
D7S82010,11
D8S117911,12
FGA22,23
Penta D9,13
Penta E7
TH019,9.3
TPOX8,9
vWA17
Web pages http://tcpaportal.org/mclp/
Publications

PubMed=1572647; DOI=10.1016/0888-7543(92)90303-A
Szepetowski P., Simon M.-P., Grosgeorge J., Huebner K., Bastard C., Evans G.A., Tsujimoto Y., Birnbaum D., Theillet C., Gaudray P.
Localization of 11q13 loci with respect to regional chromosomal breakpoints.
Genomics 12:738-744(1992)

PubMed=16448697; DOI=10.1016/j.leukres.2005.11.013
Camps J., Salaverria I., Garcia M.J., Prat E., Bea S., Pole J.C., Hernandez L., Del Rey J., Cigudosa J.C., Bernues M., Caldas C., Colomer D., Miro R., Campo E.
Genomic imbalances and patterns of karyotypic variability in mantle-cell lymphoma cell lines.
Leuk. Res. 30:923-934(2006)

PubMed=16960149; DOI=10.1182/blood-2006-06-026500
Mestre-Escorihuela C., Rubio-Moscardo F., Richter J.A., Siebert R., Climent J., Fresquet V., Beltran E., Agirre X., Marugan I., Marin M., Rosenwald A., Sugimoto K.-J., Wheat L.M., Karran E.L., Garcia J.F., Sanchez L., Prosper F., Staudt L.M., Pinkel D., Dyer M.J.S., Martinez-Climent J.A.
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Blood 109:271-280(2007)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25315077; DOI=10.3109/10428194.2014.970548
Fogli L.K., Williams M.E., Connors J.M., Reid Y.A., Brown K., O'Connor O.A.
Development and characterization of a Mantle Cell Lymphoma Cell Bank in the American Type Culture Collection.
Leuk. Lymphoma 56:2114-2122(2015)

PubMed=25355872; DOI=10.1128/JVI.02570-14
Cao S., Strong M.J., Wang X., Moss W.N., Concha M., Lin Z., O'Grady T., Baddoo M., Fewell C., Renne R., Flemington E.K.
High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project.
J. Virol. 89:713-729(2015)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections ATCC; CRL-3004
DSMZ; ACC-584
IZSLER; BS TCL 227
Cell line databases/resources CCLE; REC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
IGRhCellID; REC1
LINCS_LDP; LCL-1123
Ontologies BTO; BTO:0003558
EFO; EFO_0002317
Biological sample resources BioSample; SAMN01821592
BioSample; SAMN01821658
BioSample; SAMN03471664
Gene expression databases GEO; GSM95565
GEO; GSM95566
GEO; GSM95570
GEO; GSM104462
GEO; GSM104463
GEO; GSM115804
GEO; GSM887529
GEO; GSM888611
Polymorphism and mutation databases Cosmic; 1047111
Cosmic; 1086341
Cosmic; 1291033
Cosmic; 2088020
Cosmic; 2296993