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Cellosaurus FL (CVCL_1905)

Cell line name FL
Synonyms FL*
Accession CVCL_1905
Secondary accession CVCL_2900
Resource Identification Initiative To cite this cell line use: FL (RRID:CVCL_1905)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=20143388). Originally thought to originate from a normal amnion.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00046.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Genome sequenced (low read coverage).
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): ATCC; ECACC

Markers:
AmelogeninX
CSF1PO9,10
D13S31712,13.3 (ATCC)
12,14 (ECACC)
D16S5399,10
D5S81811,12
D7S8208,12
TH017
TPOX8,12
vWA16,18
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Publications

PubMed=13408317; DOI=10.3181/00379727-94-23003
Fogh J., Lund R.O.
Continuous cultivation of epithelial cell strain (FL) from human amniotic membrane.
Proc. Soc. Exp. Biol. Med. 94:532-537(1957)

DOI=10.1007/978-1-4757-1647-4_13
Biedler J.L.
Chromosome abnormalities in human tumor cells in culture.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=23925245; DOI=10.1038/nature12064
Adey A., Burton J.N., Kitzman J.O., Hiatt J.B., Lewis A.P., Martin B.K., Qiu R., Lee C., Shendure J.
The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line.
Nature 500:207-211(2013)

Cross-references
Cell line collections ATCC; CCL-62
ECACC; 90111910
IZSLER; BS CL 46
JCRB; JCRB9016 - Discontinued
Cell line databases/resources CLDB; cl1365
CLDB; cl1366
CLDB; cl1367
TOKU-E; 1269
Ontologies BTO; BTO:0003130
CLO; CLO_0003358
Biological sample resources BioSample; SAMN03151695
Other Wikidata; Q54834949