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Cellosaurus WISH (CVCL_1909)

Cell line name WISH
Synonyms Wistar Institute, Susan Hayflick
Accession CVCL_1909
Resource Identification Initiative To cite this cell line use: WISH (RRID:CVCL_1909)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=6451928; PubMed=20143388). Originally thought to originate from cells of the amniotic sac of Susan Hayflick, the daughter of Leonard Hayflick.
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00013.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Genome sequenced (low read coverage).
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
CVCL_8345 (ED(27))CVCL_W635 (HES [Human contaminated endometrial epithelial])
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): ATCC; JCRB; KCLB

D13S31713.3 (ATCC; JCRB; KCLB)
14 (ECACC)
D7S8208,12 (ATCC; JCRB; KCLB)
12 (ECACC)
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=WISH

PubMed=13712490; DOI=10.1016/0014-4827(61)90059-3
Hayflick L.
The establishment of a line (WISH) of human amnion cells in continuous cultivation.
Exp. Cell Res. 23:14-20(1961)

PubMed=14185313; DOI=10.1126/science.146.3641.241
Cell Culture Collection Committee
Animal cell strains. The Cell Culture Collection Committee has assembled and certified 23 strains of animal cells.
Science 146:241-243(1964)

PubMed=5641128; DOI=10.1038/217750a0
Gartler S.M.
Apparent Hela cell contamination of human heteroploid cell lines.
Nature 217:750-751(1968)

Biedler J.L.
Chromosome abnormalities in human tumor cells in culture.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=566722; DOI=10.1007/BF02616110
Lavappa K.S.
Survey of ATCC stocks of human cell lines for HeLa contamination.
In Vitro 14:469-475(1978)

PubMed=6451928; DOI=10.1126/science.6451928
Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.
Cross-contamination of cells in culture.
Science 212:446-452(1981)

Gold M.
A conspiracy of cells. One woman's immortal legacy and the medical scandal it caused.
(In) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany (1986)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=23925245; DOI=10.1038/nature12064
Adey A., Burton J.N., Kitzman J.O., Hiatt J.B., Lewis A.P., Martin B.K., Qiu R., Lee C., Shendure J.
The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line.
Nature 500:207-211(2013)

Cell line collections ATCC; CCL-25
ATCC; CRL-7727 - Discontinued
ECACC; 88102403
JCRB; IFO50004
KCLB; 10025
Cell line databases/resources CLDB; cl4720
CLDB; cl4721
CLDB; cl4723
CLDB; cl4724
CCRID; 3111C0001CCC000088
CCRID; 3131C0001000200011
CCRID; 3142C0001000000040
Ontologies BTO; BTO:0000069
CLO; CLO_0009609
Biological sample resources BioSample; SAMN03151764
Chemistry resources ChEMBL-Cells; CHEMBL3308013
ChEMBL-Targets; CHEMBL612811
Other Wikidata; Q54994114