ID   WISH
AC   CVCL_1909
SY   Wish; WISH (HeLa derivative); Wistar Institute, Susan Hayflick
DR   BTO; BTO:0000069
DR   CLO; CLO_0009609
DR   CLDB; cl4720
DR   CLDB; cl4721
DR   CLDB; cl4723
DR   CLDB; cl4724
DR   ATCC; CCL-25
DR   ATCC; CRL-7727
DR   BioSample; SAMN03151764
DR   CCRID; 1101HUM-PUMC000088
DR   CCRID; 3101HUMGNHu38
DR   ChEMBL-Cells; CHEMBL3308013
DR   ChEMBL-Targets; CHEMBL612811
DR   ECACC; 88102403
DR   IZSLER; BS CL 92
DR   JCRB; IFO50004
DR   KCLB; 10025
DR   PubChem_Cell_line; CVCL_1909
DR   Wikidata; Q54994114
RX   CelloPub=CLPUB00262;
RX   DOI=10.1007/978-1-4757-1647-4_13;
RX   DOI=10.1007/BF02618370;
RX   PubMed=566722;
RX   PubMed=1246601;
RX   PubMed=4864103;
RX   PubMed=5641128;
RX   PubMed=5668122;
RX   PubMed=6451928;
RX   PubMed=13712490;
RX   PubMed=14185313;
RX   PubMed=20143388;
RX   PubMed=22549076;
RX   PubMed=23925245;
WW   http://www.cells-talk.com/index.php/page/copelibrary?key=WISH
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=6451928; PubMed=20143388). Originally thought to originate from cells of the amniotic sac of Susan Hayflick, the daughter of Leonard Hayflick.
CC   Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00013.
CC   Population: African American.
CC   Virology: Used for differentiation of virulent and non virulent strains of measles virus (ECACC=88102403; IZSLER=BS CL 92).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: Genome sequenced (low read coverage).
CC   Discontinued: ATCC; CRL-7727; true.
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): ATCC; CCRID; ECACC; JCRB; KCLB
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 13.3 (ATCC; CCRID; JCRB; KCLB)
ST   D13S317: 14 (ECACC)
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13,14
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 8,12 (ATCC; CCRID; JCRB; KCLB)
ST   D7S820: 12 (ECACC)
ST   D8S1179: 12,13
ST   FGA: 21
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 31
//
RX   CelloPub=CLPUB00262;
RA   Gold M.;
RT   "A conspiracy of cells. One woman's immortal legacy and the medical
RT   scandal it caused.";
RL   (In) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany (1986).
//
RX   DOI=10.1007/978-1-4757-1647-4_13;
RA   Biedler J.L.;
RT   "Chromosome abnormalities in human tumor cells in culture.";
RL   (In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975).
//
RX   DOI=10.1007/BF02618370;
RA   Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.;
RT   "The animal cell culture collection.";
RL   In Vitro 5:1-16(1970).
//
RX   PubMed=566722; DOI=10.1007/BF02616110;
RA   Lavappa K.S.;
RT   "Survey of ATCC stocks of human cell lines for HeLa contamination.";
RL   In Vitro 14:469-475(1978).
//
RX   PubMed=1246601; DOI=10.1126/science.1246601;
RA   Nelson-Rees W.A., Flandermeyer R.R.;
RT   "HeLa cultures defined.";
RL   Science 191:96-98(1976).
//
RX   PubMed=4864103;
RA   Gartler S.M.;
RT   "Genetic markers as tracers in cell culture.";
RL   Natl. Cancer Inst. Monogr. 26:167-195(1967).
//
RX   PubMed=5641128; DOI=10.1038/217750a0;
RA   Gartler S.M.;
RT   "Apparent Hela cell contamination of human heteroploid cell lines.";
RL   Nature 217:750-751(1968).
//
RX   PubMed=5668122; DOI=10.3181/00379727-128-33119;
RA   Peterson W.D. Jr., Stulberg C.S., Swanborg N.K., Robinson A.R.;
RT   "Glucose-6-phosphate dehydrogenase isoenzymes in human cell cultures
RT   determined by sucrose-agar gel and cellulose acetate zymograms.";
RL   Proc. Soc. Exp. Biol. Med. 128:772-776(1968).
//
RX   PubMed=6451928; DOI=10.1126/science.6451928;
RA   Nelson-Rees W.A., Daniels D.W., Flandermeyer R.R.;
RT   "Cross-contamination of cells in culture.";
RL   Science 212:446-452(1981).
//
RX   PubMed=13712490; DOI=10.1016/0014-4827(61)90059-3;
RA   Hayflick L.;
RT   "The establishment of a line (WISH) of human amnion cells in
RT   continuous cultivation.";
RL   Exp. Cell Res. 23:14-20(1961).
//
RX   PubMed=14185313; DOI=10.1126/science.146.3641.241;
RG   Cell Culture Collection Committee;
RT   "Animal cell strains. The Cell Culture Collection Committee has
RT   assembled and certified 23 strains of animal cells.";
RL   Science 146:241-243(1964).
//
RX   PubMed=20143388; DOI=10.1002/ijc.25242;
RA   Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A.,
RA   MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R.,
RA   Freshney R.I.;
RT   "Check your cultures! A list of cross-contaminated or misidentified
RT   cell lines.";
RL   Int. J. Cancer 127:1-8(2010).
//
RX   PubMed=22549076; DOI=10.1016/j.jim.2012.04.010;
RA   Burgi M., Prieto C., Etcheverrigaray M., Kratje R., Oggero M.,
RA   Bollati-Fogolin M.;
RT   "WISH cell line: from the antiviral system to a novel reporter gene
RT   assay to test the potency of human IFN-alpha and IFN-beta.";
RL   J. Immunol. Methods 381:70-74(2012).
//
RX   PubMed=23925245; DOI=10.1038/nature12064;
RA   Adey A., Burton J.N., Kitzman J.O., Hiatt J.B., Lewis A.P.,
RA   Martin B.K., Qiu R.-L., Lee C., Shendure J.;
RT   "The haplotype-resolved genome and epigenome of the aneuploid HeLa
RT   cancer cell line.";
RL   Nature 500:207-211(2013).
//