ID   BHK-21 clone 13
AC   CVCL_1915
SY   BHK 21 clone 13; BHK21 clone 13; BHK-21 (clone 13); BHK 21 (clone 13); BHK21 (clone-13); BHK-21 (C-13); BHK-21 [C-13]; BHK-21(C-13); BHK-21(C13); BHK-21 C-13; BHK-21-C13; BHK-21/C13; BHK 21 CL13; BHK 21 C13; BHK21-C13; BHK-21 C 13; BHK 21/13; BHK21/C13; BHK21/13; BHK21 C13; BHK21C13; C13; BHK-21-ATCC
DR   CLO; CLO_0001957
DR   CLO; CLO_0001958
DR   CLO; CLO_0001959
DR   CLO; CLO_0001965
DR   CLO; CLO_0001966
DR   CLO; CLO_0001967
DR   CLO; CLO_0051403
DR   CLDB; cl439
DR   CLDB; cl444
DR   CLDB; cl445
DR   CLDB; cl446
DR   CLDB; cl447
DR   CLDB; cl448
DR   ATCC; CCL-10
DR   BCRC; 60041
DR   BCRJ; 0050
DR   CCLV; CCLV-RIE 0179
DR   CCLV; CCLV-RIE 0194
DR   CCRID; 1101HAM-PUMC000097
DR   CCRID; 1102HAM-NIFDC00033
DR   CCRID; 3101HAMGNHa10
DR   CCRID; 4201HAM-CCTCC00010
DR   CCRID; 5301HAM-KCB90020YJ
DR   CCTCC; GDC0010
DR   ChEMBL-Cells; CHEMBL3308360
DR   ChEMBL-Targets; CHEMBL614527
DR   CLS; 603126
DR   DSMZ; ACC-61
DR   DSMZCellDive; ACC-61
DR   ECACC; 85011433
DR   ECACC; 93120815
DR   FCS-free; 46-8-47-1-8-9
DR   FCS-free; 46-8-338-1-16-3
DR   IZSLER; BS CL 8
DR   JCRB; JCRB9020
DR   KCB; KCB 90020YJ
DR   KCB; KCB 92005YJ
DR   KCLB; 10010
DR   Lonza; 762
DR   NCBI_Iran; C107
DR   PubChem_Cell_line; CVCL_1915
DR   RCB; RCB1423
DR   TKG; TKG 0308
DR   TOKU-E; 667
DR   Wikidata; Q54796388
RX   DOI=10.1007/BF02618370;
RX   DOI=10.1093/jnci/30.4.795;
RX   Patent=US3228840;
RX   PubMed=4370432;
RX   PubMed=9180260;
RX   PubMed=14468055;
RX   PubMed=14207308;
RX   PubMed=19941903;
RX   PubMed=33389257;
WW   https://en.wikipedia.org/wiki/Baby_hamster_kidney_cell
WW   https://micro.magnet.fsu.edu/primer/techniques/fluorescence/gallery/cells/bhk/bhkcells.html
WW   https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-18.html
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CL-10.
CC   Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257).
CC   Doubling time: ~32-50 hours (DSMZ=ACC-61).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=10036; ! Mesocricetus auratus (Golden hamster)
HI   CVCL_1914 ! BHK-21
SX   Male
AG   1D
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 30
//
RX   DOI=10.1007/BF02618370;
RA   Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.;
RT   "The animal cell culture collection.";
RL   In Vitro 5:1-16(1970).
//
RX   DOI=10.1093/jnci/30.4.795;
RA   MacPherson I.A.;
RT   "Characteristics of a hamster cell clone transformed by polyoma virus.";
RL   J. Natl. Cancer Inst. 30:795-815(1963).
//
RX   Patent=US3228840;
RA   MacPherson I.A., Stoker M.G.P.;
RT   "Virus culture.";
RL   Patent number US3228840, 11-Jan-1966.
//
RX   PubMed=4370432; DOI=10.1016/0092-8674(74)90034-8;
RA   Shields R., Pollock K.;
RT   "The adhesion of BHK and PyBHK cells to the substratum.";
RL   Cell 3:31-38(1974).
//
RX   PubMed=9180260; DOI=10.1016/S0014-5793(97)00381-5;
RA   Jackel M., Witt C., Antonova O., Curdt I., Labeit S., Jockusch H.;
RT   "Deletion in the Z-line region of the titin gene in a baby hamster
RT   kidney cell line, BHK-21-Bi.";
RL   FEBS Lett. 408:21-24(1997).
//
RX   PubMed=14468055; DOI=10.1016/0042-6822(62)90290-8;
RA   MacPherson I.A., Stoker M.G.P.;
RT   "Polyoma transformation of hamster cell clones -- an investigation of
RT   genetic factors affecting cell competence.";
RL   Virology 16:147-151(1962).
//
RX   PubMed=14207308; DOI=10.1038/2031355a0;
RA   Stoker M.G.P., MacPherson I.A.;
RT   "Syrian hamster fibroblast cell line BHK21 and its derivatives.";
RL   Nature 203:1355-1357(1964).
//
RX   PubMed=19941903; DOI=10.1016/j.jviromet.2009.11.022;
RA   Karger A., Bettin B., Lenk M., Mettenleiter T.C.;
RT   "Rapid characterisation of cell cultures by matrix-assisted laser
RT   desorption/ionisation mass spectrometric typing.";
RL   J. Virol. Methods 164:116-121(2010).
//
RX   PubMed=33389257; DOI=10.1007/s10096-020-04106-0;
RA   Wurtz N., Penant G., Jardot P., Duclos N., La Scola B.;
RT   "Culture of SARS-CoV-2 in a panel of laboratory cell lines,
RT   permissivity, and differences in growth profile.";
RL   Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021).
//