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Cellosaurus D-17 (CVCL_1916)

Cell line name D-17
Synonyms D 17; D17
Accession CVCL_1916
Resource Identification Initiative To cite this cell line use: D-17 (RRID:CVCL_1916)
Comments Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Part of: FACC canine tumor cell line panel.
Doubling time: 22.2 hours (PubMed=22916246); 22 hours (PubMed=27257868).
Omics: Transcriptome analysis.
Disease Canine osteosarcoma (NCIt: C120045)
Derived from metastatic site: Lung.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Poodle.
Hierarchy Children:
CVCL_1917 (DAN)CVCL_1918 (DSDh)CVCL_1919 (DSN)
Sex of cell Female
Age at sampling 11Y
Category Cancer cell line
STR profile Source(s): PubMed=27197945

Markers:
Dog FHC2010231,239
Dog FHC2054156
Dog FHC2079275
Dog PEZ1127
Dog PEZ12263,290
Dog PEZ20172,180
Dog PEZ3127
Dog PEZ5103
Dog PEZ6179
Dog PEZ8232
Publications

PubMed=19147538; DOI=10.1158/1541-7786.MCR-08-0347
Zhang J., Chen X., Kent M.S., Rodriguez C.O., Chen X.
Establishment of a dog model for the p53 family pathway and identification of a novel isoform of p21 cyclin-dependent kinase inhibitor.
Mol. Cancer Res. 7:67-78(2009)

PubMed=21552385; DOI=10.7150/jca.2.262
Legare M.E., Bush J., Ashley A.K., Kato T., Hanneman W.H.
Cellular and phenotypic characterization of canine osteosarcoma cell lines.
J. Cancer 2:262-270(2011)

PubMed=21801068; DOI=10.2460/ajvr.72.8.1097
Stokol T., Daddona J.L., Mubayed L.S., Trimpert J., Kang S.-K.
Evaluation of tissue factor expression in canine tumor cells.
Am. J. Vet. Res. 72:1097-1106(2011)

PubMed=21908323; DOI=10.1177/1040638711408064
O'Donoghue L.E., Rivest J.P., Duval D.L.
Polymerase chain reaction-based species verification and microsatellite analysis for canine cell line validation.
J. Vet. Diagn. Invest. 23:780-785(2011)

PubMed=22916246; DOI=10.1371/journal.pone.0043355
Maeda J., Yurkon C.R., Fujisawa H., Kaneko M., Genet S.C., Roybal E.J., Rota G.W., Saffer E.R., Rose B.J., Hanneman W.H., Thamm D.H., Kato T.A.
Genomic instability and telomere fusion of canine osteosarcoma cells.
PLoS ONE 7:E43355-E43355(2012)

PubMed=23365669; DOI=10.1371/journal.pone.0054464
Wells J.W., Evans C.H., Scott M.C., Rutgen B.C., O'Brien T.D., Modiano J.F., Cvetkovic G., Tepic S.
Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation.
PLoS ONE 8:E54464-E54464(2013)

PubMed=27257868; DOI=10.1371/journal.pone.0156689
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=26842912; DOI=10.1111/vco.12197
Hartley G., Faulhaber E., Caldwell A., Coy J., Kurihara J., Guth A., Regan D., Dow S.
Immune regulation of canine tumour and macrophage PD-L1 expression.
Vet. Comp. Oncol. 15:534-549(2017)

PubMed=27197945; DOI=10.1111/vco.12192
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

Cross-references
Cell line collections ATCC; CCL-183
ATCC; CRL-6248 - Discontinued
ATCC; CRL-8468 - Discontinued
BCRJ; 0276
ECACC; 89090403 - Discontinued
IZSLER; BS TCL 15
NCBI_Iran; C625
Cell line databases/resources CLDB; cl954
CLDB; cl955
TOKU-E; 1025
Ontologies BTO; BTO:0005354
CLO; CLO_0002655
CLO; CLO_0002664
CLO; CLO_0002665
CLO; CLO_0002666
Gene expression databases GEO; GSM1974785
Other Wikidata; Q54817120