ID   A2780ADR
AC   CVCL_1941
SY   A2780-ADR; A2780 ADR
DR   CLO; CLO_0001572
DR   Cell_Model_Passport; SIDM01211
DR   Cosmic; 1139224
DR   ECACC; 93112520
DR   GEO; GSM827329
DR   GEO; GSM1291127
DR   Progenetix; CVCL_1941
DR   Wikidata; Q54606613
DR   Ximbio; 152707
RX   PubMed=20215515;
RX   PubMed=25230021;
CC   Part of: OCCP ovarian cancer cell line panel.
CC   Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
CC   Sequence variation: Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (PubMed=25230021).
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis.
CC   Derived from sampling site: Ovary.
ST   Source(s): ECACC; PubMed=11416159; PubMed=25230021
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 13
ST   D16S539: 11,14
ST   D18S51: 15
ST   D19S433: 12
ST   D21S11: 28
ST   D2S1338: 21,22
ST   D3S1358: 14,16
ST   D5S818: 11,12
ST   D7S820: 10
ST   D8S1179: 14,15,16,17 (PubMed=25230021)
ST   D8S1179: 15,16,17 (PubMed=11416159)
ST   FGA: 19,25
ST   Penta D: 8,9
ST   Penta E: 10,13
ST   TH01: 6 (ECACC; PubMed=25230021)
ST   TH01: 6,9.3 (PubMed=11416159)
ST   TPOX: 8,9
ST   vWA: 15,16
DI   NCIt; C7979; Ovarian endometrioid adenocarcinoma
DI   ORDO; Orphanet_454723; Endometrioid carcinoma of ovary
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0134 ! A2780
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 20-05-21; Version: 19
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
RX   PubMed=25230021; DOI=10.1371/journal.pone.0103988;
RA   Beaufort C.M., Helmijr J.C.A., Piskorz A.M., Hoogstraat M.,
RA   Ruigrok-Ritstier K., Besselink N., Murtaza M., van IJcken W.F.J.,
RA   Heine A.A.J., Smid M., Koudijs M.J., Brenton J.D., Berns E.M.J.J.,
RA   Helleman J.;
RT   "Ovarian cancer cell line panel (OCCP): clinical importance of in
RT   vitro morphological subtypes.";
RL   PLoS ONE 9:E103988-E103988(2014).