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Cellosaurus B35 (CVCL_1951)

[Text version]
Cell line name B35
Accession CVCL_1951
Resource Identification Initiative To cite this cell line use: B35 (RRID:CVCL_1951)
Comments Characteristics: Useful in the molecular analysis of endocytosis and of signaling pathways, in particular those that guide axonal outgrowth and cell motility (PubMed=12884695).
Characteristics: Can be induced to differentiate reversibly, extending long neurites when grown in low serum or treated with dibutyryl cAMP (PubMed=12884695).
Transformant: ChEBI; CHEBI_23995; N-ethyl-N-nitrosourea (ENU).
Derived from site: In situ; Central nervous system; UBERON=UBERON_0001017.
Cell type: Neuroblast; CL=CL_0000031.
Disease Rat neuroblastoma (NCIt: C121567)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: BDIX; RS=RS_0000091.
Hierarchy Children:
CVCL_E7ZL (B35 rKcnc1)CVCL_E7ZM (B35 rKcnc1 N220Q)CVCL_E7ZN (B35 rKcnc1 N220Q/N229Q)
CVCL_E7ZP (B35 rKcnc1 N229Q)
Sex of cell Sex unspecified
Age at sampling 4-10M
Category Cancer cell line
Web pages Info; -; -; https://web.archive.org/web/20150310222251/http://cellbiology.med.unsw.edu.au/units/lab/cells/cell_B35.htm
Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-211.html
Publications

PubMed=4151463; DOI=10.1038/249224a0
Schubert D., Heinemann S.F., Carlisle W., Tarikas H., Kimes B.W., Patrick J., Steinbach J.H., Culp W.J., Brandt B.L.
Clonal cell lines from the rat central nervous system.
Nature 249:224-227(1974)

PubMed=12884695; DOI=10.1016/S0091-679X(03)01013-6
Otey C.A., Boukhelifa M., Maness P.
B35 neuroblastoma cells: an easily transfected, cultured cell model of central nervous system neurons.
Methods Cell Biol. 71:287-304(2003)

PubMed=21541302; DOI=10.1371/journal.pone.0019317; PMCID=PMC3082577
Hall M.K., Cartwright T.A., Fleming C.M., Schwalbe R.A.
Importance of glycosylation on function of a potassium channel in neuroblastoma cells.
PLoS ONE 6:e19317.1-e19317.11(2011)

Cross-references
Cell line collections (Providers) ATCC; CRL-2754
Cell line databases/resources CLO; CLO_0001815
Lonza; 1397
TOKU-E; 596
Anatomy/cell type resources BTO; BTO_0002649
Encyclopedic resources Wikidata; Q54752661
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number22