ID   B9
AC   CVCL_1952
DR   CLO; CLO_0001836
DR   CLDB; cl360
DR   CLDB; cl4929
DR   CLDB; cl5051
DR   ATCC; CRL-2344
DR   DSMZ; ACC-211
DR   DSMZCellDive; ACC-211
DR   ECACC; 12121201
DR   ECACC; 96080128
DR   ICLC; HYL98004
DR   IZSLER; BS Hy 55
DR   Wikidata; Q54752865
RX   PubMed=3263920;
RX   PubMed=3500054;
RX   PubMed=7730664;
RX   PubMed=8034982;
RX   PubMed=8267637;
RX   PubMed=8398901;
WW   http://www.cells-talk.com/index.php/page/copelibrary?key=B9
CC   Characteristics: Used for measuring the biological activity of IL6. This is called the B9 hybridoma assay.
CC   Characteristics: IL6 dependent.
CC   Doubling time: ~30-50 hours (DSMZ=ACC-211).
CC   Monoclonal antibody isotype: IgG1.
CC   Monoclonal antibody target: Human antigen on mature granulocytes.
CC   Discontinued: ATCC; CRL-2344; true.
CC   Discontinued: ECACC; 96080128; probable.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_B953 ! B13.29
CA   Hybridoma
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 15
//
RX   PubMed=3263920; DOI=10.1002/eji.1830181010;
RA   Helle M., Boeije L., Aarden L.A.;
RT   "Functional discrimination between interleukin 6 and interleukin 1.";
RL   Eur. J. Immunol. 18:1535-1540(1988).
//
RX   PubMed=3500054; DOI=10.1002/eji.1830171004;
RA   Aarden L.A., De Groot E.R., Schaap O.L., Lansdorp P.M.;
RT   "Production of hybridoma growth factor by human monocytes.";
RL   Eur. J. Immunol. 17:1411-1416(1987).
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RX   PubMed=7730664; DOI=10.1016/0022-1759(94)00323-o;
RA   Labit-Le Bouteiller C., Astruc R., Minty A., Ferrara P., Lupker J.H.;
RT   "Isolation of an IL-13-dependent subclone of the B9 cell line useful
RT   for the estimation of human IL-13 bioactivity.";
RL   J. Immunol. Methods 181:29-36(1995).
//
RX   PubMed=8034982; DOI=10.1016/0022-1759(94)90278-x;
RA   Lu Z.-Y., Zhang X.-G., Gu Z.-J., Yasukawa K., Amiot M., Etrillard M.,
RA   Bataille R., Klein B.;
RT   "A highly sensitive quantitative bioassay for human interleukin-11.";
RL   J. Immunol. Methods 173:19-26(1994).
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RX   PubMed=8267637; DOI=10.1006/bbrc.1993.2576;
RA   Nishihara T., Okahashi N., Ueda N.;
RT   "Activin A induces apoptotic cell death.";
RL   Biochem. Biophys. Res. Commun. 197:985-991(1993).
//
RX   PubMed=8398901;
RA   Yin T.-G., Yang Y.-C.;
RT   "Protein tyrosine phosphorylation and activation of primary response
RT   genes by interleukin 11 in B9-TY1 cells.";
RL   Cell Growth Differ. 4:603-609(1993).
//